AKR1A1

Gene Symbol AKR1A1
Entrez Gene 10327
Alt Symbol ALDR1, ALR, ARM, DD3, HEL-S-6
Species Human
Gene Type protein-coding
Description aldo-keto reductase family 1, member A1 (aldehyde reductase)
Other Description HEL-S-165mP|alcohol dehydrogenase|alcohol dehydrogenase [NADP(+)]|aldehyde reductase|aldo-keto reductase family 1 member A1|dihydrodiol dehydrogenase 3|epididymis secretory protein Li 6|epididymis secretory sperm binding protein Li 165mP
Swissprots Q6IAZ4 P14550 D3DQ04 A8KAL8
Accessions AAB92369 AAF01260 EAX06970 EAX06971 EAX06972 EAX06973 EAX06974 P14550 AK293083 BAF85772 AK307068 AK307237 AK307288 AK311175 AU142853 BC000670 AAH00670 BC005394 AAH05394 BC033287 BI549149 BT007003 AAP35649 BU631634 CR457010 CAG33291 CX788871 DA550374 DA871469 DQ890682 ABM81608 DQ893770 ABM84696 DQ893865 ABM84791 EU668319 ACF94472 EU794588 ACJ13642 J04794 AAA51711 XM_011540491 XP_011538793 XM_011540492 XP_011538794 XR_946517 NM_001202414 NP_001189343 NM_006066 NP_006057 NM_153326 NP_697021 NM_001202413 NP_001189342
Function Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4- nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D- glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotics and drugs, including the anthracyclines doxorubicin (DOX) and daunorubicin (DAUN). {ECO:0000269|PubMed:10510318, ECO:0000269|PubMed:11306097, ECO:0000269|PubMed:18276838}.
Tissue Specificity Widely expressed. Highly expressed in kidney, salivary gland and liver. Detected in trachea, stomach, brain, lung, prostate, placenta, mammary gland, small intestine and lung. {ECO:0000269|PubMed:10510318, ECO:0000269|PubMed:11306097}.
Top Pathways Glycolysis / Gluconeogenesis, Pentose and glucuronate interconversions, Glycerolipid metabolism, Degradation of aromatic compounds

Human Alcohol Dehydrogenase ELISA Kit - abx052986 from Abbexa

Category ELISA Kit
Sensitivity 1 ng/L
Range 5 ng/L - 150 ng/L

Alcohol dehydrogenase [NADP+] (AKR1A1), Human, ELISA Kit - E01A1368 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Alcohol Dehydrogenase, Human, ELISA Kit - E01A0736 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t
Sensitivity 0.1ng/ml
Range 0.5-10 ng/mL,

AKR1A1 (Human) Matched Antibody Pair - H00010327-AP22 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

Alcohol Dehydrogenase, ELISA Kit - MBS031513 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alcohol Dehydrogenase, ELISA Kit - MBS028210 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alcohol Dehydrogenase, ELISA Kit - MBS062005 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alcohol Dehydrogenase, ELISA Kit - MBS087353 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alcohol Dehydrogenase, ELISA Kit - MBS016752 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alcohol Dehydrogenase, ELISA Kit - MBS083900 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alcohol Dehydrogenase, ELISA Kit - MBS105965 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alcohol Dehydrogenase, ELISA Kit - MBS728562 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1 ng/mL.

Mouse AKR1A1 ELISA Kit (Competitive EIA) - LS-F28202 from LifeSpan Bioscience

Category ELISA Kit
Prices $870.00
Sizes 1 plate
Sensitivity 0.1 ng/ml
Range 0.5-10 ng/ml

Rat AKR1A1 ELISA Kit (Competitive EIA) - LS-F27875 from LifeSpan Bioscience

Category ELISA Kit
Prices $870.00
Sizes 1 plate
Sensitivity 1 ng/ml
Range 0.5-10 ng/ml

Human AKR1A1 ELISA Kit (Competitive EIA) - LS-F27644 from LifeSpan Bioscience

Category ELISA Kit
Prices $870.00
Sizes 1 plate
Sensitivity 0.1 ng/ml
Range 0.5-10 ng/ml

Human AKR1A1 ELISA Kit - E001275 from Biobool

Category ELISA Kit

anti-Alcohol Dehydrogenase antibody [1E5] - ARG10343 from Arigo Biolaboratories

Category ELISA Kit

Alcohol Dehydrogenase (ADH), ELISA Kit - MBS9375786 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alcohol Dehydrogenase (Human) ELISA Kit - E4514 from Biovision

Category ELISA Kit
Prices $695.00
Sizes 100 assays
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