SERPING1

Gene Symbol	SERPING1
Entrez Gene	710
Alt Symbol	C1IN, C1INH, C1NH, HAE1, HAE2
Species	Human
Gene Type	protein-coding
Description	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Other Description	C1 esterase inhibitor\|C1-inhibiting factor\|complement component 1 inhibitor\|plasma protease C1 inhibitor\|serine/cysteine proteinase inhibitor clade G member 1\|serpin G1
Swissprots	Q7Z455 Q9UCF9 B4E1F0 B2R6L5 Q96FE0 A6NMU0 B4E1H2 Q9UC49 Q59EI5 A8KAI9 Q16304 Q547W3 P05155
Accessions	AAA53096 AAB33044 AAM21515 AAQ19269 AAW69393 CAA30314 CAA38358 EAW73762 EAW73763 EAW73764 P05155 AB209826 BAD93063 AK293054 BAF85743 AK303809 BAG64762 AK303840 BAG64784 AK312626 BAG35512 AL703442 AY732485 AAV33124 AY732486 AAV33125 BC011171 AAH11171 BQ183346 BT006966 AAP35612 DQ891799 ABM82725 DQ894982 ABM85908 GU727623 ADU87625 M13203 AAA51849 M13656 AAB59387 M13690 AAA35613 M14036 AAA51848 X07577 CAA30469 NM_000062 NP_000053 NM_001032295 NP_001027466
Function	Activation of the C1 complex is under control of the C1- inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. {ECO:0000269\|PubMed:8495195}.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades, Pertussis

C1INH (H-300) - sc-67150 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

C1INH (H-300): sc-67150. Western blot analysis of C1INH expression in non-transfected: sc-110760 (A) and human C1INH transfected: sc-112306 (B) 293 whole cell lysates.

C1INH (B-11) - sc-377062 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

C1INH (B-11): sc-377062. Immunoperoxidase staining of formalin fixed, paraffin-embedded human adrenal gland tissue showing cytoplasmic staining of glandular cells.

C1INH (K-16) - sc-46298 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

C1INH (K-16): sc-46298. Western blot analysis of C1INH expression in non-transfected: sc-110760 (A) and human C1INH transfected: sc-112306 (B) 293 whole cell lysates.

C1INH (K-15) - sc-46297 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

C1INH (K-15): sc-46297. Western blot analysis of C1INH expression in non-transfected: sc-117752 (A) and mouse C1INH transfected: sc-126534 (B) 293T whole cell lysates.

Anti-C1 Inactivator antibody - ab54898 from Abcam

Prices	$378.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

C1 Inactivator antibody (ab54898) used in immunohistochemistry at 1ug/ml on formalin fixed and paraffin embedded human kidney.

Anti-C1 Inactivator antibody - ab180774 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-C1 Inactivator antibody (ab180774) at 1/500 dilutionLane 1 : HL60 cell lysateLane 2 : DU145 cell lysateLane 3 : SW480 cell lysateLane 4 : MCF7 cell lysateLane 5 : HeLa cell lysateLane 6 : HepG2 cell lysate

Anti-C1 Inactivator antibody - ab97348 from Abcam

Prices	$376.00
Sizes	50 µl
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-C1 Inactivator antibody (ab97348) at 1/1000 dilutionLane 1 : 293T whole cell lysateLane 2 : HeLa S3 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-C1 Inactivator antibody [4G12] - ab36992 from Abcam

Host	Mouse
Clonality	Monoclonal
Clone	4G12

All lanes : Anti-C1 Inactivator antibody [4G12] (ab36992)Lane 1 : C1 inhibitor isolated from Human plasmaLane 2 : Human plasmaLysates/proteins at 50 µg per lane.Secondaryanti-mouse IgG -HRP

Anti-C1 Inactivator antibody [EPR8015] - ab134918 from Abcam

Prices	$378.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR8015

All lanes : Anti-C1 Inactivator antibody [EPR8015] (ab134918) at 1/1000 dilutionLane 1 : Human serum lysateLane 2 : Human plasma lysateLysates/proteins at 10 µg per lane.SecondaryGoat-anti-rabbit HRP at 1/2000 dilution

Anti-C1 Inactivator antibody [EPR8016] - ab134915 from Abcam

Prices	$378.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR8016

All lanes : Anti-C1 Inactivator antibody [EPR8016] (ab134915) at 1/1000 dilutionLane 1 : Human plasma lysateLane 2 : Human serum lysateLysates/proteins at 10 µg per lane.SecondaryHRP-conjugated goat anti-rabbit IgG at 1/2000 dilution

Anti-C1 Inactivator antibody [KT28] - ab53365 from Abcam

Prices	$368.00
Sizes	500 µg
Host	Mouse
Clonality	Monoclonal
Clone	KT28

Anti-C1 Inactivator antibody [M81] - ab81707 from Abcam

Prices	$381.00
Sizes	50 µg
Host	Mouse
Clonality	Monoclonal
Clone	M81

ab81707, at a dilution of 1/50, staining paraffin embedded human liver melanoma cells by Immunohistochemistry. Insert is isotype control.

Anti-C1 Inactivator antibody - BSA and Azide free - ab182949 from Abcam

Host	Goat
Clonality	Polyclonal

Anti-C1 Inactivator antibody - BSA and Azide free - ab182954 from Abcam

Prices	$370.00
Sizes	1 ml
Host	Rabbit
Clonality	Polyclonal

Anti-C1 Esterase Inhibitor Antibody - LS-C147224 from LifeSpan Bioscience

Prices	$285.00
Sizes	1 ml
Host	Goat
Clonality	Polyclonal

Anti-C1 Esterase Inhibitor Antibody - LS-C147771 from LifeSpan Bioscience

Prices	$285.00
Sizes	1 ml
Host	Rabbit
Clonality	Polyclonal

Anti-C1 Esterase Inhibitor Antibody (HRP) - LS-C193854 from LifeSpan Bioscience

Prices	$530.00
Sizes	200 µg
Host	Goat
Clonality	Polyclonal

Anti-SERPING1 / C1 Inhibitor Antibody (aa211-331, Biotin) - LS-C298310 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SERPING1 / C1 Inhibitor Antibody (aa399-500) - LS-C292407 from LifeSpan Bioscience

Prices	$395.00
Sizes	200 µg
Host	Mouse
Clonality	Monoclonal

Western blot of recombinant SERPING1 / C1 Inhibitor.

Anti-SERPING1 / C1 Inhibitor Antibody (aa211-331) - LS-C293463 from LifeSpan Bioscience

Prices	$385.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SERPING1 / C1 Inhibitor Antibody (aa148-270, Biotin) - LS-C298312 from LifeSpan Bioscience

Prices	$425.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SERPING1 / C1 Inhibitor Antibody (aa399-500) - LS-C293465 from LifeSpan Bioscience

Prices	$385.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SERPING1 / C1 Inhibitor Antibody (aa399-500, Biotin) - LS-C299105 from LifeSpan Bioscience

Prices	$405.00
Sizes	200 µg
Host	Mouse
Clonality	Monoclonal

Anti-SERPING1 / C1 Inhibitor Antibody (aa35-179, Biotin) - LS-C299929 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SERPING1 / C1 Inhibitor Antibody (aa397-495, Biotin) - LS-C299927 from LifeSpan Bioscience

Prices	$405.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

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