SERPING1

Gene Symbol	SERPING1
Entrez Gene	710
Alt Symbol	C1IN, C1INH, C1NH, HAE1, HAE2
Species	Human
Gene Type	protein-coding
Description	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Other Description	C1 esterase inhibitor|C1-inhibiting factor|complement component 1 inhibitor|plasma protease C1 inhibitor|serine/cysteine proteinase inhibitor clade G member 1|serpin G1
Swissprots	Q7Z455 Q9UCF9 B4E1F0 B2R6L5 Q96FE0 A6NMU0 B4E1H2 Q9UC49 Q59EI5 A8KAI9 Q16304 Q547W3 P05155
Accessions	AAA53096 AAB33044 AAM21515 AAQ19269 AAW69393 CAA30314 CAA38358 EAW73762 EAW73763 EAW73764 P05155 AB209826 BAD93063 AK293054 BAF85743 AK303809 BAG64762 AK303840 BAG64784 AK312626 BAG35512 AL703442 AY732485 AAV33124 AY732486 AAV33125 BC011171 AAH11171 BQ183346 BT006966 AAP35612 DQ891799 ABM82725 DQ894982 ABM85908 GU727623 ADU87625 M13203 AAA51849 M13656 AAB59387 M13690 AAA35613 M14036 AAA51848 X07577 CAA30469 NM_000062 NP_000053 NM_001032295 NP_001027466
Function	Activation of the C1 complex is under control of the C1- inhibitor. It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Inhibits chymotrypsin and kallikrein. {ECO:0000269|PubMed:8495195}.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades, Pertussis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

C1INH CRISPR/Cas9 KO Plasmid (h) - sc-403065 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

C1INH HDR Plasmid (h) - sc-403065-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

C1INH Double Nickase Plasmid (h) - sc-403065-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

C1INH Double Nickase Plasmid (h2) - sc-403065-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

C1INH CRISPR Activation Plasmid (h) - sc-403065-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

C1INH CRISPR Activation Plasmid (h2) - sc-403065-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

C1INH Lentiviral Activation Particles (h) - sc-403065-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

C1INH Lentiviral Activation Particles (h2) - sc-403065-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

C1INH siRNA (h) - sc-45608 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

C1INH shRNA Plasmid (h) - sc-45608-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

C1INH shRNA (h) Lentiviral Particles - sc-45608-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Serpin G1/C1 Inhibitor RNAi - H00000710-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

Serpin G1/C1 Inhibitor RNAi - H00000710-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU099601 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® esiRNA - EHU159531 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1615 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1615 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02183 from Sigma-Aldrich Category miRNA

SERPING1 siRNA (Human) - CRH0490 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SERPING1 - MBS8222506 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human SERPING1 (NM_000062.2) - SHH405408 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human SERPING1(NM_001032295.1) - SHR218040 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human SERPING1(NM_000062.2) - SHR218058 from Creative biogene Category siRNA Species Reactivities Human

Human SERPING1 siRNA - orb260992 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SERPING1 shRNA Plasmid (Human) - CHH0490 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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