Gene Symbol |
Chrnb1
|
Entrez Gene |
24261
|
Alt Symbol |
Acrb, RNACRB1
|
Species |
Rat
|
Gene Type |
protein-coding
|
Description |
cholinergic receptor, nicotinic, beta 1 (muscle)
|
Other Description |
Acetylcholine receptor beta|acetylcholine receptor subunit beta|cholinergic receptor nicotinic beta polypeptide 1|cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
|
Swissprots |
P25109
|
Accessions |
EDM04893 P25109 X74833 CAA52827 XM_008767770 XP_008765992 NM_012528 NP_036660
|
Function |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
|
Subcellular Location |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
|
Top Pathways |
Neuroactive ligand-receptor interaction
|