Gene Symbol | Chrnb1 |
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Entrez Gene | 24261 |
Alt Symbol | Acrb, RNACRB1 |
Species | Rat |
Gene Type | protein-coding |
Description | cholinergic receptor, nicotinic, beta 1 (muscle) |
Other Description | Acetylcholine receptor beta|acetylcholine receptor subunit beta|cholinergic receptor nicotinic beta polypeptide 1|cholinergic receptor, nicotinic, beta polypeptide 1 (muscle) |
Swissprots | P25109 |
Accessions | EDM04893 P25109 X74833 CAA52827 XM_008767770 XP_008765992 NM_012528 NP_036660 |
Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
Subcellular Location | Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. |
Top Pathways | Neuroactive ligand-receptor interaction |
CompoZr® Knockout ZFN Kit - CKOZFN52037 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND52037 from Sigma-Aldrich
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CHRNB1 siRNA (Rat) - CRR0064 from Cohesion Biosciences
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CHRNB1 - MBS8206291 from MyBioSource
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shRNA set against Rat CHRNB1 (NM_012528.1) - SHH263629 from Creative biogene
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shRNA set against Rat Chrnb1(NM_012528.1) - SHG177427 from Creative biogene
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Rat CHRNB1 siRNA - orb294913 from Biorbyt
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CHRNB1 shRNA Plasmid (Rat) - CHR0064 from Cohesion Biosciences
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CHRNB1 miRNA 3'UTR clone - MiUTR1R-00988 from Creative biogene
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