ADRBK1

Gene Symbol	ADRBK1
Entrez Gene	156
Alt Symbol	BARK1, BETA-ARK1, GRK2
Species	Human
Gene Type	protein-coding
Description	adrenergic, beta, receptor kinase 1
Other Description	G-protein coupled receptor kinase 2|beta-ARK-1|beta-adrenergic receptor kinase 1
Swissprots	P25098 B0ZBE1 Q6GTT3 Q13837
Accessions	AAB60689 ACA05909 EAW74581 EAW74582 P25098 AB209588 BAD92825 AI888604 AK131506 BC037963 AAH37963 BC090863 AAH90863 DN989901 DQ891148 ABM82074 DQ894328 ABM85254 M80776 AAA58391 X61157 CAA43470 XM_011544773 XP_011543075 XR_949796 NM_001619 NP_001610
Function	Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. {ECO:0000269|PubMed:19306925}.
Subcellular Location	Cytoplasm {ECO:0000250|UniProtKB:P21146}. Cell membrane {ECO:0000250|UniProtKB:P21146}.
Tissue Specificity	Expressed in peripheral blood leukocytes. {ECO:0000269|PubMed:10085131}.
Top Pathways	Endocytosis, Chemokine signaling pathway, Glutamatergic synapse, Morphine addiction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human/Rat ADRBK1 / GRK2 ELISA Kit (Cell-Based ELISA) - LS-F3075 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.313-20 ng/ml

Mouse/Human/Rat Phospho-ADRBK1 / GRK2 (Ser685) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1720 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.313-20 ng/ml

Mouse/Human/Rat ADRBK1 / GRK2 ELISA Kit (Cell-Based ELISA) - LS-F2028 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.313-20 ng/ml

Mouse/Human/Rat Phospho-ADRBK1 / GRK2 (Ser29) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1172 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.313-20 ng/ml

Human ADRBK1 / GRK2 ELISA Kit (Sandwich ELISA) - LS-F9317 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.313 ng/ml Range 0.313-20 ng/ml

Human ADRbK1 ELISA Kit - abx150577 from Abbexa Category ELISA Kit Sensitivity 0.105 ng/ml Range 0.313 ng/ml - 20 ng/ml

Adrenergic Receptor Beta Kinase 1 (ADRbK1), Human, ELISA Kit - SEC189Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.105ng/mL Range 0.312-20ng/mL

Beta-adrenergic receptor kinase 1 (ADRBK1), Human, ELISA Kit - CSB-EL001394HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 4.68 pg/ml Range 18.75 pg/ml-1200 pg/ml

Beta-adrenergic receptor kinase 1 (ADRBK1), Human, ELISA Kit - E01B0729 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

GRK2 Colorimetric Cell-Based ELISA Kit - CB5306 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

ARBK1 Colorimetric Cell-Based ELISA - CB5863 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

GRK2 (Phospho-Ser29) Colorimetric Cell-Based ELISA Kit - CBP1161 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

GRK2 (Phospho-Ser685) Colorimetric Cell-Based ELISA Kit - CBP1803 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Adrenergic Receptor Beta 1 (ADRb1), ELISA Kit - MBS2023691 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of rat ADRb1 is typically less than 0.055ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.156-10ng/mL

Adrenergic Receptor Beta 1 (ADRb1), ELISA Kit - MBS2019231 from MyBioSource Category ELISA Kit Prices $385.00, $575.00, $785.00, $3,210.00, $5,825.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.059ng/mL. Range 0.156-10ng/mL

Adrenergic Receptor Beta Kinase 1 (ADRbK1), ELISA Kit - MBS2023802 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of ADRbK1 is typically less than 0.125ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.312-20ng/mL

adrenergic, beta, receptor kinase 1, ELISA Kit - MBS925953 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 4.68 pg/ml Range 18.75 pg/ml-1200 pg/ml

beta adrenergic receptor kinase 1 (ADRBK1), ELISA Kit - MBS7209250 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Beta-adrenergic receptor kinase 1 (ADRBK1), ELISA Kit - MBS7210505 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beta-adrenergic receptor kinase 1 (ADRBK1), ELISA Kit - MBS7244332 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beta-adrenergic receptor kinase 1 (ADRBK1), ELISA Kit - MBS7238199 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Beta-adrenergic receptor kinase 1 (ADRBK1), ELISA Kit - MBS7232577 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beta-adrenergic receptor kinase 1 (ADRBK1), ELISA Kit - MBS7247687 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beta-adrenergic receptor kinase 1 (ADRBK1), ELISA Kit - MBS7210890 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Beta-adrenergic receptor kinase 1 (ADRBK1), ELISA Kit - MBS7248302 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

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