Gene Symbol | Vcam1 |
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Entrez Gene | 22329 |
Alt Symbol | CD106, Vcam-1 |
Species | Mouse |
Gene Type | protein-coding |
Description | vascular cell adhesion molecule 1 |
Other Description | V-CAM 1|vascular cell adhesion protein 1 |
Swissprots | P29533 |
Accessions | AAA16920 AAA16921 AAA80010 AAA80011 AAA80012 AAA80013 AAA80014 AAA80015 AAA80016 AAB60659 AAB60660 AAB60661 AAB60662 AAB60663 AAB60664 AAB88576 EDL12388 EDL12389 P29533 AK016465 AK030195 BAC26834 AK078081 AK085320 AK143401 BAE25364 AK162954 BAE37132 AK169722 BC011159 AAH11159 BC029823 AAH29823 CT010373 CAJ18580 L08431 AAA40546 L12541 AAC37607 M84487 AAA40545 U12884 AAA64832 X67783 CAA47989 NM_011693 NP_035823 |
Function | Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. |
Subcellular Location | Isoform 1: Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue. Expressed in the bone marrow. {ECO:0000269|PubMed:1713592}. |
Top Pathways | Leukocyte transendothelial migration, Cell adhesion molecules (CAMs), Malaria, African trypanosomiasis, HTLV-I infection |
Recombinant Mouse VCAM-1/CD106 Fc Chimera, CF - 643-VM-050 from R&D Systems
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Recombinant Mouse VCAM-1/CD106 Fc Chimera, CF - 643-VM-200 from R&D Systems
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Mouse VCAM1 Protein - abx069623 from Abbexa
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Mouse VCAM1 Protein - abx069626 from Abbexa
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CD106 / VCAM1 - H00007412-Q01-10 from Acris Antibodies
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CD106 / VCAM1 - H00007412-Q01-25 from Acris Antibodies
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Vascular Cell Adhesion Molecule 1 (VCAM1), Mouse - 20-6764 from ARP American Research Products
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Vascular Cell Adhesion Molecule 1 (VCAM1), Mouse - 20-6765 from ARP American Research Products
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Recombinant Mouse VCAM1, MIgG2a Fc-tagged - VCAM1-1793M from Creative Biomart
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Recombinant Mouse Vcam1, His tagged - Vcam1-4012M from Creative Biomart
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Recombinant Mouse Vcam1, Fc-His tagged - Vcam1-2313M from Creative Biomart
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Recombinant Mouse Vascular Cell Adhesion Molecule 1 - Vcam1-1784M from Creative Biomart
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Recombinant Mouse Vcam1, Fc Chimera - Vcam1-491M from Creative Biomart
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Recombinant Mouse Vcam1, His-tagged - Vcam1-4013M from Creative Biomart
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Mouse VCAM1 / CD106 Protein (His & Fc Tag) - 50163-M03H-100 from Sino Biological
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Mouse VCAM1 / L1CAM / CD106 Protein (His Tag) - 50163-M08H-100 from Sino Biological
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Recombinant Vascular Cell Adhesion Molecule 1 (VCAM1) - RPA547Mu01 from Cloud-clone
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Recombinant Vascular Cell Adhesion Molecule 1 (VCAM1) - RPA547Mu02 from Cloud-clone
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Recombinant Mouse Vascular cell adhesion protein 1(Vcam1) - CSB-YP025809MO CSB-EP025809MO CSB-BP025809MO CSB-MP025809MO from Cusabio
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Recombinant Mouse VCAM-1/CD106 Fc Chimera Protein, CF - 643-VM from R&D Systems
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Recombinant Human VCAM-1/CD106 Protein, CF - ADP5 from R&D Systems
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Vascular cell adhesion protein 1, 25-698aa, Mouse, His tag, Baculovirus - ATGP3246 from ATGen
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Vascular Cell Adhesion Molecule 1 (VCAM1) - RPU144308 from Biomatik
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Vascular Cell Adhesion Molecule 1 (VCAM1) - RPU144311 from Biomatik
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CD106 / VCAM1 (25-698, His-tag) - AR52001PU-N from Acris Antibodies
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