Gene Symbol |
Hpn
|
Entrez Gene |
15451
|
Alt Symbol |
Hlb320
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
hepsin
|
Other Description |
serine protease hepsin
|
Swissprots |
B2RSC4 O35453 Q9CW97
|
Accessions |
EDL23952 EDL23953 EDL23954 O35453 AF030065 AAB84221 AK002694 BAB22289 AK156553 BAE33755 AY234104 AAP58478 BC138809 AAI38810 BC145413 AAI45414 CA534405 CB949755 CJ237993 CN668960 NM_001110252 NP_001103722 NM_001276269 NP_001263198 NM_008281 NP_032307
|
Function |
May mediate the activating cleavage of HGF and MST1/HGFL. Plays a role in the proteolytic processing of ACE2 (By similarity). Plays an essential role in cell growth and maintenance of cell morphology. {ECO:0000250}.
|
Subcellular Location |
Membrane; Single-pass type II membrane protein.
|
Top Pathways |
Viral carcinogenesis
|