Gene Symbol | Hpn |
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Entrez Gene | 15451 |
Alt Symbol | Hlb320 |
Species | Mouse |
Gene Type | protein-coding |
Description | hepsin |
Other Description | serine protease hepsin |
Swissprots | B2RSC4 O35453 Q9CW97 |
Accessions | EDL23952 EDL23953 EDL23954 O35453 AF030065 AAB84221 AK002694 BAB22289 AK156553 BAE33755 AY234104 AAP58478 BC138809 AAI38810 BC145413 AAI45414 CA534405 CB949755 CJ237993 CN668960 NM_001110252 NP_001103722 NM_001276269 NP_001263198 NM_008281 NP_032307 |
Function | May mediate the activating cleavage of HGF and MST1/HGFL. Plays a role in the proteolytic processing of ACE2 (By similarity). Plays an essential role in cell growth and maintenance of cell morphology. {ECO:0000250}. |
Subcellular Location | Membrane; Single-pass type II membrane protein. |
Top Pathways | Viral carcinogenesis |
Hepsin CRISPR/Cas9 KO Plasmid (m) - sc-420942 from Santa Cruz Biotechnology
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Hepsin HDR Plasmid (m) - sc-420942-HDR from Santa Cruz Biotechnology
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Hepsin Double Nickase Plasmid (m) - sc-420942-NIC from Santa Cruz Biotechnology
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Hepsin Double Nickase Plasmid (m2) - sc-420942-NIC-2 from Santa Cruz Biotechnology
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Hepsin CRISPR Activation Plasmid (m) - sc-420942-ACT from Santa Cruz Biotechnology
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Hepsin CRISPR Activation Plasmid (m2) - sc-420942-ACT-2 from Santa Cruz Biotechnology
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Hepsin Lentiviral Activation Particles (m) - sc-420942-LAC from Santa Cruz Biotechnology
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Hepsin Lentiviral Activation Particles (m2) - sc-420942-LAC-2 from Santa Cruz Biotechnology
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Hepsin siRNA (m) - sc-41657 from Santa Cruz Biotechnology
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Hepsin shRNA Plasmid (m) - sc-41657-SH from Santa Cruz Biotechnology
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Hepsin shRNA (m) Lentiviral Particles - sc-41657-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU083381 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN33444 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND33444 from Sigma-Aldrich
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HPN siRNA (Mouse) - CRM1913 from Cohesion Biosciences
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HPN - MBS8234899 from MyBioSource
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shRNA set against Mouse HPN (NM_008281.3) - SHH314621 from Creative biogene
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shRNA set against Mouse Hpn(NM_008281.3) - SHH130169 from Creative biogene
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shRNA set against Mouse Hpn(NM_001110252.1) - SHH130187 from Creative biogene
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HPN shRNA Plasmid (Mouse) - CHM1913 from Cohesion Biosciences
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HPN miRNA 3'UTR clone - MiUTR1M-05773 from Creative biogene
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HPN miRNA 3'UTR clone - MiUTR1M-05774 from Creative biogene
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