Gene Symbol | MGAT5 |
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Entrez Gene | 4249 |
Alt Symbol | GNT-V, GNT-VA |
Species | Human |
Gene Type | protein-coding |
Description | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase |
Other Description | N-acetylglucosaminyl-transferase V|alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A|alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase|glcNAc-T V|mannoside acetylglucosaminyltransferase 5 |
Swissprots | Q09328 D3DP70 |
Accessions | AAB81939 AAX93248 AAY14747 AAY14791 EAX11657 EAX11658 Q09328 AF055029 AF113921 AAD22449 AK056461 AK125207 BC041917 BC156313 AAI56314 BC157048 AAI57049 BU191961 BX647087 D17716 BAA04570 DB223638 DB237089 XM_005263668 XP_005263725 XM_005263669 XP_005263726 XM_005263670 XP_005263727 XM_006712534 XP_006712597 XM_006712535 XP_006712598 XM_011511199 XP_011509501 XM_011511200 XP_011509502 XM_011511201 XP_011509503 XM_011511202 XP_011509504 XM_011511203 XP_011509505 XM_011511204 XP_011509506 NM_002410 NP_002401 |
Function | Catalyzes the addition of N-acetylglucosamine in beta 1- 6 linkage to the alpha-linked mannose of biantennary N-linked oligosaccharides. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. |
Subcellular Location | Golgi apparatus membrane; Single-pass type II membrane protein. |
Top Pathways | N-Glycan biosynthesis |
GnT-V CRISPR/Cas9 KO Plasmid (h) - sc-403921 from Santa Cruz Biotechnology
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GnT-V HDR Plasmid (h) - sc-403921-HDR from Santa Cruz Biotechnology
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GnT-V Double Nickase Plasmid (h) - sc-403921-NIC from Santa Cruz Biotechnology
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GnT-V Double Nickase Plasmid (h2) - sc-403921-NIC-2 from Santa Cruz Biotechnology
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GnT-V CRISPR Activation Plasmid (h) - sc-403921-ACT from Santa Cruz Biotechnology
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GnT-V CRISPR Activation Plasmid (h2) - sc-403921-ACT-2 from Santa Cruz Biotechnology
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GnT-V Lentiviral Activation Particles (h) - sc-403921-LAC from Santa Cruz Biotechnology
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GnT-V Lentiviral Activation Particles (h2) - sc-403921-LAC-2 from Santa Cruz Biotechnology
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GnT-V siRNA (h) - sc-40642 from Santa Cruz Biotechnology
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GnT-V shRNA Plasmid (h) - sc-40642-SH from Santa Cruz Biotechnology
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GnT-V shRNA (h) Lentiviral Particles - sc-40642-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN13278 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13278 from Sigma-Aldrich
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MGAT5 siRNA (Human) - CRH2889 from Cohesion Biosciences
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N-Acetylglucosaminyltransferase V/MGAT5 RNAi - H00004249-R01 from Novus Biologicals
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Human MGAT5 siRNA - orb263391 from Biorbyt
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MGAT5 shRNA Plasmid (Human) - CHH2889 from Cohesion Biosciences
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