| Gene Symbol |
Prcp
|
| Entrez Gene |
72461
|
| Alt Symbol |
2510048K03Rik, 2610104A14Rik, AI451719, HUMPCP, PCP
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
prolylcarboxypeptidase (angiotensinase C)
|
| Other Description |
lysosomal Pro-X carboxypeptidase|proline carboxypeptidase
|
| Swissprots |
Q8R0T8 Q3V302 Q3TLW3 Q9D049 Q8BKK3 Q7TMR0
|
| Accessions |
EDL06718 Q7TMR0 AK011112 AK011816 BAB27858 AK030160 AK051677 BAC34716 AK054462 BAE20697 AK083719 AK166282 BAE38679 BC026424 AAH26424 BC055022 AAH55022 BC089575 XM_011241910 XP_011240212 NM_028243 NP_082519
|
| Function |
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Lysosome {ECO:0000250}.
|
| Top Pathways |
Protein digestion and absorption
|