PTPRC

Gene Symbol PTPRC
Entrez Gene 5788
Alt Symbol B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
Species Human
Gene Type protein-coding
Description protein tyrosine phosphatase, receptor type, C
Other Description CD45 antigen|T200 glycoprotein|T200 leukocyte common antigen|protein tyrosine phosphatase, receptor type, c polypeptide|receptor-type tyrosine-protein phosphatase C
Swissprots Q9H0Y6 P08575 Q16614 A8K7W6
Accessions AAA59497 AAD15273 AAG26082 AAM12758 AAS46922 AAS46930 AAS46938 AAS46946 AAS46954 AAS46962 CBU30438 CBU83087 EAW91300 EAW91301 EAW91302 EAW91303 P08575 AA403163 AA904360 AK130573 AK292131 BAF84820 AK299986 BAG61807 AK303539 BAG64565 AK307635 AK308217 AK310898 AY429565 AY429566 AY567999 AAS75254 BC014239 AAH14239 BC017863 AAH17863 BC031525 BC121086 AAI21087 BC121087 AAI21088 BC127656 AAI27657 BC127657 AAI27658 BC148257 AAI48258 BC169206 BC169207 BM791051 DA670254 DA819314 DA948670 Y00062 CAA68269 Y00638 CAA68669 XM_006711472 XP_006711535 XM_006711473 XP_006711536 XM_006711474 XP_006711537 NM_001267798 NP_001254727 NM_002838 NP_002829 NM_080921 NP_563578 NR_052021 NM_080922
Function Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity). {ECO:0000250}.
Subcellular Location Membrane {ECO:0000269|PubMed:12676959}; Single-pass type I membrane protein {ECO:0000269|PubMed:12676959}. Membrane raft {ECO:0000269|PubMed:12676959}. Note=Colocalized with DPP4 in membrane rafts.
Top Pathways T cell receptor signaling pathway, Cell adhesion molecules (CAMs), Primary immunodeficiency, Fc gamma R-mediated phagocytosis

Cluster of differentiation 45 (CD45), Human, ELISA Kit - CSB-E17497h from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Cluster of differentiation 45 (CD45), Human, ELISA Kit - E01C2410 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t
Sensitivity 0.1ng/ml
Range 1.0-25ng/ml

Leukocyte Common Antigen, LCA/CD45, Human, ELISA Kit - YHB1860Hu from ARP American Research Products

Category ELISA Kit

Receptor-type tyrosine-protein phosphatase C, PTPRC, Human, ELISA Kit - E1030h from ARP American Research Products

Category ELISA Kit
Prices $596.00
Sizes 96 t

cluster of differentiation 45 (CD45), ELISA Kit - MBS7211493 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

leukocyte common antigen (LCA), ELISA Kit - MBS265067 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

leukocyte common antigen (LCA), ELISA Kit - MBS265839 from MyBioSource

Category ELISA Kit
Prices $290.00, $450.00, $1,755.00, $3,150.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

leukocyte common antigen (LCA), ELISA Kit - MBS261500 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

leukocyte common antigen (LCA), ELISA Kit - MBS261274 from MyBioSource

Category ELISA Kit
Prices $290.00, $450.00, $1,755.00, $3,150.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

leukocyte common antigen (LCA), ELISA Kit - MBS2602187 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

leukocyte common antigen (LCA), ELISA Kit - MBS265458 from MyBioSource

Category ELISA Kit
Prices $315.00, $490.00, $1,825.00, $3,425.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

leukocyte common antigen, LCA/CD45, ELISA Kit - MBS9302061 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1 ng/ml
Range 0.5 ng/ml - 16 ng/ml

cluster of differentiation 45 (CD45), ELISA Kit - MBS7233538 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

cluster of differentiation 45 (CD45), ELISA Kit - MBS7207710 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

cluster of differentiation 45 (CD45), ELISA Kit - MBS7236425 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

cluster of differentiation 45 (CD45), ELISA Kit - MBS7233139 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.0 ng/mL.

cluster of differentiation 45 (CD45), ELISA Kit - MBS7211895 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

cluster of differentiation 45 (CD45), ELISA Kit - MBS7245436 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

cluster of differentiation 45 (CD45), ELISA Kit - MBS7233963 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

cluster of differentiation 45 (CD45), ELISA Kit - MBS7242674 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

cluster of differentiation 45 (CD45), ELISA Kit - MBS7226822 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

cluster of differentiation 45 (CD45), ELISA Kit - MBS7253470 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

protein tyrosine phosphatase, receptor type, C, ELISA Kit - MBS704384 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.039 ng/ml
Range 0.156 ng/ml-10 ng/ml

CD45, Human - DP-10057-X from Nordic BioSite

Human cluster of differentiation 45(CD45) ELISA Kit - CSB-E17497h from Cusabio

Category ELISA Kit
Sensitivity 0.039 ng/ml
Range 0.156 ng/ml-10 ng/ml
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