EPOR

Gene Symbol EPOR
Entrez Gene 2057
Alt Symbol EPO-R
Species Human
Gene Type protein-coding
Description erythropoietin receptor
Other Description -
Swissprots Q2M205 B2RCG4 P19235 Q15443
Accessions AAA52392 AAA52393 AAB23271 AAB34703 ABX71216 AFM52330 AFM52331 EAW84205 EAW84206 EAW84207 EAW84208 P19235 AK315097 BAG37561 BC019092 BC112153 AAI12154 BC143697 BC143698 BC143700 BU619338 M34986 AAA52401 M60459 AAA52403 X57282 CAA40550 X97671 CAA66260 NM_000121 NP_000112 NR_033663
Function Receptor for erythropoietin. Mediates erythropoietin- induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.
Subcellular Location Cell membrane; Single-pass type I membrane protein.
Tissue Specificity Erythroid cells and erythroid progenitor cells. Isoform EPOR-F is the most abundant form in EPO-dependent erythroleukemia cells and in late-stage erythroid progenitors. Isoform EPOR-S and isoform EPOR-T are the predominant forms in bone marrow. Isoform EPOR-T is the most abundant from in early- stage erythroid progenitor cells.
Top Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, PI3K-Akt signaling pathway

EpoR (D-5) - sc-365662 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
EpoR (D-5): sc-365662. Western blot analysis of EpoR expression in GM-CSF treated K-562 (A) and Jurkat (B) whole cell lysates.

EpoR (G-14) - sc-82590 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

EpoR (H-194) - sc-5624 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
EpoR (H-194): sc-5624. Immunoperoxidase staining of formalin fixed, paraffin-embedded mouse liver tissue showing membrane localization.

EpoR (M-20) - sc-697 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
EpoR (M-20): sc-697. Immunofluorescence staining of methanol-fixed K-562 cells showing membrane staining.

EpoR (W-20) - sc-82593 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

EpoR (C-20) - sc-695 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
EpoR (C-20): sc-695. Western blot analysis of EpoR expression in K-562 (A) and Jurkat (B) whole cell lysates.

Anti-EPO Receptor (phospho Y368) antibody - ab193235 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EPO Receptor (phospho Y368) antibody (ab193235) at 1/500 dilutionLane 1 : K562 extractLane 2 : K562 extract with antigen-specific peptide

Anti-EPO Receptor (phospho Y368) antibody - ab195775 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EPO Receptor (phospho Y368) antibody (ab195775) at 1/500 dilutionLane 1 : K562 whole cell lysate with antigen-specific peptideLane 2 : K562 whole cell lysateLysates/proteins at 12.5 µg per lane.

Anti-EPO Receptor (phospho Y368) antibody - ab61792 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EPO Receptor (phospho Y368) antibody (ab61792) at 1/500 dilutionLane 1 : K562 cell extractsLane 2 : K562 cell extracts with immunising peptide

Anti-EPO Receptor (phospho Y485) antibody [EPR2266] - ab79824 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2266
All lanes : Anti-EPO Receptor (phospho Y485) antibody [EPR2266] (ab79824) at 1/50000 dilutionLane 1 : MCF-7 cell lysate untreatedLane 2 : MCF-7 cell lysate treated with pervanadateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP conjugate at 1/2000 dilution

Anti-EPO Receptor antibody - ab10653 from Abcam

Prices $378.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-EPO Receptor antibody - ab61162 from Abcam

Prices $379.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab166162 staining EPO Receptor in NIH3T3 cell line from Mouse fibroblasts by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with paraformaldehyde, permeabilized with Triton X-100 0.1% and blocked with 10% serim for 60 minutes at 24°C. Samples were incubated with primary antibody (1/100) for 16 hour at 4°C. An Alexa Fluor®488-conjugated Donkey anti-rabbit polyclonal(1/500) was used as the secondary antibody.See Abreview

Anti-EPO Receptor antibody - ab183104 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Telomerase reverse transcriptase antibody - C-terminal (ab183105) at 1/500 dilutionLane 1 : 231 cell lysateLane 2 : 293T cell lysateLane 3 : Hela cell lysateLysates/proteins at 40 µg per lane.SecondaryGoat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution

Anti-EPO Receptor antibody - ab54659 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-EPO Receptor antibody [MM-0031-6G7] - ab56310 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM-0031-6G7
Formalin fixed and Paraffin embedded human placenta tissue section was subjected to IHC staining using ab56310 (Proteinase K pretreatment is required).

Anti-EPO Receptor antibody [MM0350-6A33] - ab135206 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone MM0350-6A33

Anti-EPO Receptor antibody [VP2E8] - ab180791 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone VP2E8
Flow cytometric staining of BOSC23 cells transiently transfected with an expression vector encoding either EPO Receptor (red curve) or an irrelevant protein black curve (control transfectant) labeling EPO receptor  with ab180791 at 1/200 dilution. A PE conjugated secondary antibody was used. A positive signal was obtained only with EPO receptor transfected cells.

Anti-EPOR / EPO Receptor Antibody (clone 12K92, PE) - LS-C182846 from LifeSpan Bioscience

Prices $575.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal
Clone 12K92

Anti-EPOR / EPO Receptor Antibody (aa31-131, clone 10C138, Azide-free) - LS-C183605 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 10C138

Anti-EPOR / EPO Receptor Antibody (aa26-250, clone 1D4B) - LS-C189802 from LifeSpan Bioscience

Prices $605.00
Sizes 500 µg
Host Mouse
Clonality Monoclonal
Clone 1D4B

Anti-EPOR / EPO Receptor Antibody (clone 1D4B) - LS-C189803 from LifeSpan Bioscience

Prices $475.00
Sizes 100 tst
Host Mouse
Clonality Monoclonal
Clone 1D4B

Anti-EPOR / EPO Receptor Antibody (Extracellular Domain) - LS-C187856 from LifeSpan Bioscience

Prices $310.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-EPOR / EPO Receptor Antibody (phospho-Tyr426, clone 1D4B) - LS-C189804 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D4B

Anti-EPOR / EPO Receptor Antibody (phospho-Tyr485, clone EPR2266) - LS-C105536 from LifeSpan Bioscience

Prices $450.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR2266
Western blot analysis on MCF-7 cell lysates using anti-Phospho-EpoR (pY485) antibody (LS-C105536), 1:50000 dilution. Cells were either (A) untreated (B) treated with pervanadate.

Anti-EPOR / EPO Receptor Antibody (Ser423) - LS-C193239 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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