Gene Symbol | Tnfrsf13b |
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Entrez Gene | 57916 |
Alt Symbol | 1200009E08Rik, Taci |
Species | Mouse |
Gene Type | protein-coding |
Description | tumor necrosis factor receptor superfamily, member 13b |
Other Description | transmembrane activator and CAML interactor|transmembrane activator and calcium-modulating and cyclophilin ligand interactor|tumor necrosis factor receptor superfamily member 13B |
Swissprots | Q9DBZ3 Q9ET35 |
Accessions | CAF03581 CAJ90565 CAJ90570 CBY65606 Q9ET35 AF257673 AAG00081 AK004668 BAB23457 AK155178 BAE33096 BC139392 AAI39393 BC139393 AAI39394 BC141867 AAI41868 BC141868 AAI41869 XM_006533851 XP_006533914 XM_006533852 XP_006533915 NM_021349 NP_067324 |
Function | Receptor for TNFSF13/APRIL and TNFSF13B/TALL1/BAFF/BLYS that binds both ligands with similar high affinity. Mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-kappa-B and AP-1. Involved in the stimulation of B- and T- cell function and the regulation of humoral immunity (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type III membrane protein {ECO:0000305}. |
Top Pathways | Cytokine-cytokine receptor interaction, Primary immunodeficiency, Intestinal immune network for IgA production |
TACI CRISPR/Cas9 KO Plasmid (m) - sc-425465 from Santa Cruz Biotechnology
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TACI HDR Plasmid (m) - sc-425465-HDR from Santa Cruz Biotechnology
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TACI Double Nickase Plasmid (m) - sc-425465-NIC from Santa Cruz Biotechnology
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TACI Double Nickase Plasmid (m2) - sc-425465-NIC-2 from Santa Cruz Biotechnology
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TACI CRISPR Activation Plasmid (m) - sc-425465-ACT from Santa Cruz Biotechnology
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TACI CRISPR Activation Plasmid (m2) - sc-425465-ACT-2 from Santa Cruz Biotechnology
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TACI Lentiviral Activation Particles (m) - sc-425465-LAC from Santa Cruz Biotechnology
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TACI Lentiviral Activation Particles (m2) - sc-425465-LAC-2 from Santa Cruz Biotechnology
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TACI siRNA (m) - sc-40244 from Santa Cruz Biotechnology
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TACI shRNA Plasmid (m) - sc-40244-SH from Santa Cruz Biotechnology
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TACI shRNA (m) Lentiviral Particles - sc-40244-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN43228 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND43228 from Sigma-Aldrich
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TNFRSF13B siRNA (Mouse) - CRM6081 from Cohesion Biosciences
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TNFRSF13B - MBS8231211 from MyBioSource
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shRNA set against Mouse TNFRSF13B (NM_021349.1) - SHH431912 from Creative biogene
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shRNA set against Mouse Tnfrsf13b(NM_021349.1) - SHL084732 from Creative biogene
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Mouse TNFRSF13B siRNA - orb285557 from Biorbyt
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TNFRSF13B shRNA Plasmid (Mouse) - CHM6081 from Cohesion Biosciences
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TNFRSF13B miRNA 3'UTR clone - MiUTR1M-11987 from Creative biogene
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