| Gene Symbol |
ZWILCH
|
| Entrez Gene |
55055
|
| Alt Symbol |
KNTC1AP, hZwilch
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
zwilch kinetochore protein
|
| Other Description |
Zwilch, kinetochore associated, homolog|homolog of Drosophila Zwilch|protein zwilch homolog
|
| Swissprots |
Q96SY7 Q8N404 Q9NWG7 B3KVB8 Q9H900 Q6N049
|
| Accessions |
EAW77777 EAW77778 EAW77779 Q9H900 AK000898 AK023175 BAB14446 AK027468 BAB55133 AK122787 BAG53730 AK291048 BAF83737 BC036900 AAH36900 BC090041 AAH90041 BQ775697 BX640701 CAE45821 NR_003105 NM_001287821 NP_001274750 NM_001287822 NP_001274751 NM_001287823 NP_001274752 NM_017975 NP_060445
|
| Function |
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. {ECO:0000269|PubMed:15824131}.
|
| Subcellular Location |
Chromosome, centromere, kinetochore {ECO:0000269|PubMed:20462495}.
|
