ALOX5

Gene Symbol	ALOX5
Entrez Gene	240
Alt Symbol	5-LO, 5-LOX, 5LPG, LOG5
Species	Human
Gene Type	protein-coding
Description	arachidonate 5-lipoxygenase
Other Description	LOX-5|arachidonic 5-lipoxygenase alpha-10 isoform|arachidonic 5-lipoxygenase delta-10-13 isoform|arachidonic 5-lipoxygenase delta-13 isoform|arachidonic 5-lipoxygenase delta-p10 isoform|arachidonic acid 5-lipoxygenase|leukotriene A4 synthase
Swissprots	E5FPY7 B7ZLS0 E5FPY5 P09917 Q5JQ14 E5FPY8
Accessions	AAA59522 AAA63212 EAW86642 EAW86643 P09917 AB208946 BAD92183 AK225603 AK315223 AW403395 BC034464 BC040450 BC130332 AAI30333 BC132677 AAI32678 BC143985 AAI43986 BC143986 BM153780 BQ003253 HM592258 ADR30798 HM592259 ADR30799 HM592260 ADR30800 HM592261 ADR30801 HQ258335 ADR83089 J03571 AAA65450 J03600 AAA36183 JQ728550 AFH78150 XM_011539564 XP_011537866 XM_011546981 XP_011545283 NM_000698 NP_000689 NM_001256153 NP_001243082 NM_001256154 NP_001243083
Function	Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes. {ECO:0000269|PubMed:21233389}.
Subcellular Location	Cytoplasm. Nucleus matrix. Nucleus membrane; Peripheral membrane protein. Note=Shuttles between cytoplasm and nucleus. Found exclusively in the nucleus, when phosphorylated on Ser-272. Calcium binding promotes translocation from the cytosol and the nuclear matrix to the nuclear envelope and membrane association.
Top Pathways	Toxoplasmosis, Ovarian steroidogenesis, Arachidonic acid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human 5 Lipoxygenase full length protein - ab114310 from Abcam Category Protein Prices $420.00 Sizes 10 µg Source Wheat germ Species Human

ALOX5 / 5-Lipoxygenase Antibody Blocking Peptide - LS-E26158 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

5-Lipoxygenase Blocking Peptide - NB110-58749PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg Species Human

5-Lipoxygenase Blocking Peptide - NB110-58748PEP from Novus Biologicals Category Peptide Prices $69.00 Sizes 50 µg Species Human

Recombinant Human 5-Lipoxygenase Protein - H00000240-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

ALOX5-Antibody-Center-Blocking-Peptide - BP7856c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

5-Lipoxygenase blocking peptide - GTX89250-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat

5 Lipoxygenase Peptide - AC21-0988-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

ALOX5 / LOG5 - H00000240-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

ALOX5 / LOG5 - H00000240-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Arachidonate 5-lipoxygenase Peptide - 45-274P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human, Rat

ALOX5 fusion protein - ag19503 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

ALOX5 fusion protein - Ag18168 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human Arachidonate 5-lipoxygenase 1 - ALOX5-723H from Creative Biomart Category Protein Source S. fruigiperda.

Recombinant Human Arachidonate 5-lipoxygenase 1 - ALOX5-578H from Creative Biomart Category Protein Source Sf21 cells .

Recombinant Human Arachidonate 5-lipoxygenase - ALOX5-696H from Creative Biomart Category Protein Source Sf21 .

Recombinant Arachidonate-5-Lipoxygenase (ALOX5) - RPB355Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Arachidonate-5-Lipoxygenase (ALOX5) - RPB355Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Arachidonate-5-Lipoxygenase (ALOX5) - RPB355Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Arachidonate-5-Lipoxygenase (ALOX5) - RPB355Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

5-Lipoxygenase, Human, Recombinant, S. fruigiperda - 437996 from EMD Millipore Species Human

ALOX5 (E267) Peptide - BS1506P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Arachidonate-5-Lipoxygenase (ALOX5) - RPB355Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Arachidonate 5-lipoxygenase(ALOX5) - CSB-YP001624HU CSB-EP001624HU CSB-BP001624HU CSB-MP001624HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Phospho-ALOX5-S271 Peptide - abx165111 from Abbexa Category Peptide Species Human

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