CNOT2

Gene Symbol CNOT2
Entrez Gene 4848
Alt Symbol CDC36, HSPC131, NOT2, NOT2H
Species Human
Gene Type protein-coding
Description CCR4-NOT transcription complex, subunit 2
Other Description CCR4-NOT transcription complex subunit 2|CCR4-associated factor 2|negative regulator of transcription 2
Swissprots Q9NSX5 Q9P028 Q9NWR6 Q9H3E0 Q9NZN8
Accessions EAW97245 EAW97246 EAW97247 EAW97248 EAW97249 Q9NZN8 AA234384 AF044215 AAQ13426 AF113226 AAG39297 AF161480 AAF29095 AF180473 AAF29827 AK000662 BAA91313 AK095789 BAG53128 AK129966 BAC85263 AK307479 AK315715 BAG38074 AL137674 CAB70869 AY395696 AAR32245 BC002597 AAH02597 BC011826 AAH11826 BX641116 CAE46054 DA445519 DB038192 EU446948 ABZ92477 XM_006719429 XP_006719492 XM_006719430 XP_006719493 XM_006719432 XP_006719495 XM_006719433 XP_006719496 XM_011538399 XP_011536701 XM_011538400 XP_011536702 XM_011538401 XP_011536703 NM_001199302 NP_001186231 NM_001199303 NP_001186232 NM_014515 NP_055330 NR_037615
Function Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem (ES) cell identity. {ECO:0000269|PubMed:14707134, ECO:0000269|PubMed:16712523, ECO:0000269|PubMed:21299754, ECO:0000269|PubMed:22367759}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:21299754}. Nucleus {ECO:0000305|PubMed:21299754}.
Tissue Specificity Ubiquitous. Highly expressed in brain, heart, thymus, spleen, kidney, liver, small intestine, placenta, lung and peripheral blood leukocytes. {ECO:0000269|PubMed:10637334}.
Top Pathways RNA degradation

Mouse/Human/Rat CNOT2 ELISA Kit (Cell-Based ELISA) - LS-F1895 from LifeSpan Bioscience

Category ELISA Kit
Prices $450.00
Sizes 1 plate

CCR4-NOT transcription complex subunit 2 (CNOT2), Human, ELISA Kit - E01C1858 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t
Sensitivity 1.0pg/ml
Range 50-1000pg/ml

CNOT2 Colorimetric Cell-Based ELISA Kit - CB5150 from Assay Biotechnology

Category ELISA Kit
Prices $380.00, $760.00, $1,140.00
Sizes 1 kit, 2 kits, 3 kits
Range > 5000 Cells

CCR4-NOT transcription complex subunit 2 (CNOT2), ELISA Kit - MBS7246598 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 2 (CNOT2), ELISA Kit - MBS7233543 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 2 (CNOT2), ELISA Kit - MBS7206427 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 2 (CNOT2), ELISA Kit - MBS7237674 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 2 (CNOT2), ELISA Kit - MBS7207982 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 2 (CNOT2), ELISA Kit - MBS7246916 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 2 (CNOT2), ELISA Kit - MBS7219579 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 2 (CNOT2), ELISA Kit - MBS7215253 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 2 (CNOT2), ELISA Kit - MBS7227342 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 2 (CNOT2), ELISA Kit - MBS7217109 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 2 (CNOT2), ELISA Kit - MBS7225316 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CNOT2 ELISA Kit - DEIA-XYA436 from Creative Diagnostics

Category ELISA Kit

Human CNOT2 ELISA Kit - E007238 from Biobool

Category ELISA Kit

CNOT2 Colorimetric Cell-Based ELISA Kit - EKA50130 from Biomatik

Category ELISA Kit
Prices $399.00
Sizes 96 tests
Sensitivity At least 5000 cells/well
Range Qualitative
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