| Gene Symbol |
Lama3
|
| Entrez Gene |
16774
|
| Alt Symbol |
Lama3B, [a]3B
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
laminin, alpha 3
|
| Other Description |
epiligrin subunit alpha|kalinin subunit alpha|laminin subunit alpha-3|laminin-5 subunit alpha|laminin-6 subunit alpha|laminin-7 subunit alpha|nicein subunit alpha|nicein, 150kDa
|
| Swissprots |
O08751 Q9JHQ7 Q61966 Q61788 E9PUR4 Q61789
|
| Accessions |
CAA70073 Q61789 AJ293592 CAB99254 AK138740 BAE23763 AK141255 L20478 AAA68091 U88353 AAC53179 X84013 CAA58836 X84014 CAA58837 XM_006525685 XP_006525748 XM_006525686 XP_006525749 XM_006525687 XP_006525750 XM_006525688 XP_006525751 XM_006525689 XP_006525752 XM_006525690 XP_006525753 XM_006525691 XP_006525754 XR_385977 NM_010680 NP_034810
|
| Function |
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
|
| Subcellular Location |
Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
|
| Tissue Specificity |
Basal membrane of the upper alimentary tract and urinary and nasal epithelia, salivary glands and teeth (both variants). Isoform A is predominantly expressed in skin, hair follicles and developing neurons of the trigeminal ganglion. Isoform B was found in bronchi, alveoli, stomach, intestinal crypts, whisker pads, CNS, telencephalic neuroectoderm, thalamus, Rathke pouch and periventricular subependymal germinal layer.
|
| Top Pathways |
Focal adhesion, ECM-receptor interaction, Small cell lung cancer, Amoebiasis, Toxoplasmosis
|