| Gene Symbol | Lama3 |
|---|---|
| Entrez Gene | 16774 |
| Alt Symbol | Lama3B, [a]3B |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | laminin, alpha 3 |
| Other Description | epiligrin subunit alpha|kalinin subunit alpha|laminin subunit alpha-3|laminin-5 subunit alpha|laminin-6 subunit alpha|laminin-7 subunit alpha|nicein subunit alpha|nicein, 150kDa |
| Swissprots | O08751 Q9JHQ7 Q61966 Q61788 E9PUR4 Q61789 |
| Accessions | CAA70073 Q61789 AJ293592 CAB99254 AK138740 BAE23763 AK141255 L20478 AAA68091 U88353 AAC53179 X84013 CAA58836 X84014 CAA58837 XM_006525685 XP_006525748 XM_006525686 XP_006525749 XM_006525687 XP_006525750 XM_006525688 XP_006525751 XM_006525689 XP_006525752 XM_006525690 XP_006525753 XM_006525691 XP_006525754 XR_385977 NM_010680 NP_034810 |
| Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
| Subcellular Location | Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component. |
| Tissue Specificity | Basal membrane of the upper alimentary tract and urinary and nasal epithelia, salivary glands and teeth (both variants). Isoform A is predominantly expressed in skin, hair follicles and developing neurons of the trigeminal ganglion. Isoform B was found in bronchi, alveoli, stomach, intestinal crypts, whisker pads, CNS, telencephalic neuroectoderm, thalamus, Rathke pouch and periventricular subependymal germinal layer. |
| Top Pathways | Focal adhesion, ECM-receptor interaction, Small cell lung cancer, Amoebiasis, Toxoplasmosis |
Laminin α-3 CRISPR/Cas9 KO Plasmid (m) - sc-421376 from Santa Cruz Biotechnology
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Laminin α-3 HDR Plasmid (m) - sc-421376-HDR from Santa Cruz Biotechnology
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Laminin α-3 Double Nickase Plasmid (m) - sc-421376-NIC from Santa Cruz Biotechnology
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Laminin α-3 Double Nickase Plasmid (m2) - sc-421376-NIC-2 from Santa Cruz Biotechnology
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Laminin α-3 CRISPR Activation Plasmid (m) - sc-421376-ACT from Santa Cruz Biotechnology
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Laminin α-3 CRISPR Activation Plasmid (m2) - sc-421376-ACT-2 from Santa Cruz Biotechnology
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Laminin α-3 Lentiviral Activation Particles (m) - sc-421376-LAC from Santa Cruz Biotechnology
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Laminin α-3 Lentiviral Activation Particles (m2) - sc-421376-LAC-2 from Santa Cruz Biotechnology
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Laminin α-3 siRNA (m) - sc-43146 from Santa Cruz Biotechnology
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Laminin α-3 shRNA Plasmid (m) - sc-43146-SH from Santa Cruz Biotechnology
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Laminin α-3 shRNA (m) Lentiviral Particles - sc-43146-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU146411 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN34596 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND34596 from Sigma-Aldrich
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LAMA3 siRNA (Mouse) - CRM2294 from Cohesion Biosciences
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shRNA set against Mouse LAMA3 (NM_010680.1) - SHH328227 from Creative biogene
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shRNA set against Mouse Lama3(NM_010680.1) - SHH141355 from Creative biogene
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Mouse LAMA3 siRNA - orb281770 from Biorbyt
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LAMA3 shRNA Plasmid (Mouse) - CHM2294 from Cohesion Biosciences
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LAMA3 miRNA 3'UTR clone - MiUTR1M-06511 from Creative biogene
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