NTN1

Gene Symbol	NTN1
Entrez Gene	9423
Alt Symbol	NTN1L
Species	Human
Gene Type	protein-coding
Description	netrin 1
Other Description	epididymis tissue protein Li 131P|netrin 1, mouse, homolog of|netrin-1
Swissprots	E9KL51 O95631
Accessions	EAW90032 O95631 BC092429 GU727649 ADU87650 U75586 AAD09221 XM_006721595 XP_006721658 NM_004822 NP_004813
Function	Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis. {ECO:0000269|PubMed:15343335}.
Subcellular Location	Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Tissue Specificity	Widely expressed in normal adult tissues with highest levels in heart, small intestine, colon, liver and prostate. Reduced expression in brain tumors and neuroblastomas. Expressed in epididymis (at protein level). {ECO:0000269|PubMed:20736409, ECO:0000269|PubMed:9950216}.
Top Pathways	Axon guidance

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Netrin 1 protein fragment - ab152983 from Abcam Category Protein Source Wheat germ Species Human

Mouse Netrin 1 peptide - ab91607 from Abcam Category Peptide

Netrin 1 peptide - ab192272 from Abcam Category Peptide

NTN1 / Netrin 1 Antibody Blocking Peptide - LS-E25985 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Netrin-1 Protein - H00009423-Q01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Netrin 1 blocking peptide - GTX88460-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

Recombinant Human Netrin-1 - 6419-N1-025 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Recombinant Human Netrin-1, CF - 6419-N1-025/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

NTN1 peptide - orb218252 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse

Netrin 1 Blocking Peptide - abx063583 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

Netrin 1 Peptide - AC21-0813-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Netrin-1 - H00009423-Q01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

Netrin-1 Control Peptide - AP05263CP-N from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

Netrin-1 Control Peptide - AP10176CP-N from Acris Antibodies Category Peptide Prices $235.00 Sizes 250 µg

Netrin 1 (Ntn1), Human - 20-8064 from ARP American Research Products Category Protein Prices $519.00 Sizes 50 µg Source E.coli Species Human

NTN1 Peptide - 42-733P from ProSci Category Peptide Species Rat

Recombinant Human NTN1, Fc-tagged - NTN1-428H from Creative Biomart Category Protein Source HEK293 Cells Species Human

Recombinant Human NTN1 - NTN1-1088H from Creative Biomart Category Protein Source NSO Cells Species Human

Recombinant Human Netrin 1, FLAG-tagged - NTN1-2173H from Creative Biomart Category Protein Source HEK 293.

Recombinant Netrin 1 (Ntn1) - RPB827Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Netrin 1 (Ntn1) - RPB827Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Netrin 1 (Ntn1) - RPB827Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Netrin 1 (Ntn1) - RPB827Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Netrin 1 (Ntn1) - RPB827Ga01 from Uscn Life Science Inc. Category Protein Source E.coli Species Chicken

Netrin 1 Blocking Peptide - CBP2389 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Monkey

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