NTN1

Gene Symbol NTN1
Entrez Gene 9423
Alt Symbol NTN1L
Species Human
Gene Type protein-coding
Description netrin 1
Other Description epididymis tissue protein Li 131P|netrin 1, mouse, homolog of|netrin-1
Swissprots E9KL51 O95631
Accessions EAW90032 O95631 BC092429 GU727649 ADU87650 U75586 AAD09221 XM_006721595 XP_006721658 NM_004822 NP_004813
Function Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis. {ECO:0000269|PubMed:15343335}.
Subcellular Location Secreted, extracellular space, extracellular matrix {ECO:0000250}.
Tissue Specificity Widely expressed in normal adult tissues with highest levels in heart, small intestine, colon, liver and prostate. Reduced expression in brain tumors and neuroblastomas. Expressed in epididymis (at protein level). {ECO:0000269|PubMed:20736409, ECO:0000269|PubMed:9950216}.
Top Pathways Axon guidance

netrin-1 CRISPR/Cas9 KO Plasmid (h) - sc-401871 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

netrin-1 HDR Plasmid (h) - sc-401871-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

netrin-1 Double Nickase Plasmid (h) - sc-401871-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

netrin-1 Double Nickase Plasmid (h2) - sc-401871-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

netrin-1 CRISPR Activation Plasmid (h) - sc-401871-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

netrin-1 CRISPR Activation Plasmid (h2) - sc-401871-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

netrin-1 Lentiviral Activation Particles (h) - sc-401871-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

netrin-1 Lentiviral Activation Particles (h2) - sc-401871-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

netrin-1 siRNA (h) - sc-42044 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

netrin-1 shRNA Plasmid (h) - sc-42044-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

netrin-1 shRNA (h) Lentiviral Particles - sc-42044-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN15562 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15562 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NTN1 siRNA (Human) - CRH6249 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NTN1 (NM_004822.2) - SHH355700 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human NTN1(NM_004822.2) - SHR024792 from Creative biogene

Category siRNA
Species Reactivities Human

NTN1 shRNA Plasmid (Human) - CHH6249 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NTN1 miRNA 3'UTR clone - MiUTR1H-06944 from Creative biogene

Species Reactivities Human
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