HLA-DMA

Gene Symbol HLA-DMA
Entrez Gene 3108
Alt Symbol D6S222E, DMA, HLADM, RING6
Species Human
Gene Type protein-coding
Description major histocompatibility complex, class II, DM alpha
Other Description HLA class II histocompatibility antigen, DM alpha chain|MHC class II antigen DMA|class II histocompatibility antigen, M alpha chain|really interesting new gene 6 protein
Swissprots P28067 Q29639 Q29640
Accessions AAA56993 AAA56994 AHW47929 AHW47946 AHW47963 AHW47980 BAA31432 CAA54169 CAA54170 CAA60781 EAX03658 EAX03659 EAX03660 P28067 AA649861 AK291858 BAF84547 AK298081 BAH12721 AU100342 BC011447 AAH11447 BC026279 AAH26279 CR450324 CAG29320 DQ892839 ABM83765 DQ896086 ABM87085 X62744 CAA44606 NM_006120 NP_006111
Function Plays a critical role in catalyzing the release of class II-associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO. {ECO:0000269|PubMed:16547258, ECO:0000269|PubMed:8849454, ECO:0000269|PubMed:9768757}.
Subcellular Location Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Localizes to late endocytic compartment. Associates with lysosome membranes.
Top Pathways Leishmaniasis, HTLV-I infection, Influenza A, Tuberculosis, Herpes simplex infection

HLA-DMA-Over-expression-Lysate - LY12673a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag HLA-DMA (arrow) using his tag antibody. 293T cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the HLA-DMA gene

HLA-DMA 293T Cell Transient Overexpression Lysate(Denatured) - H00003108-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

HLA 293 Cell Lysate - 407877 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

HLA DMA Overexpression Lysate (Denatured) - H00003108-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
HLA-DMA transfected lysate

HLA DMA Overexpression Lysate (Native) - NBL1-11591 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

HLA-DMα (h): 293T Lysate - sc-159308 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

HLA Over-expression Lysate Product - GWB-B84575 from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human HLA-DMA Knockdown Stable Cell Line - CSC-DC007087 from Creative biogene

Category Cell Line
Species Human
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