WHSC1

Gene Symbol WHSC1
Entrez Gene 7468
Alt Symbol MMSET, NSD2, REIIBP, TRX5, WHS
Species Human
Gene Type protein-coding
Description Wolf-Hirschhorn syndrome candidate 1
Other Description IL5 promoter REII region-binding protein|histone-lysine N-methyltransferase NSD2|multiple myeloma SET domain containing protein type III|nuclear SET domain-containing protein 2|probable histone-lysine N-methyltransferase NSD2|trithorax/ash1-related protein 5
Swissprots Q86V01 A7MCZ1 A2A2T2 Q4VBY8 Q9UPR2 Q9BZB4 A2A2T4 Q6IS00 O96028 O96031 Q672J1 Q9UI92 A2A2T3 D3DVQ2
Accessions AAF23369 AAF23370 EAW82548 EAW82549 EAW82550 EAW82551 EAW82552 EAW82553 EAW82554 EAW82555 EAW82556 EAW82557 EAW82558 O96028 AB029013 BAA83042 AF071593 AAC24150 AF071594 AAC24151 AF083386 AAD19343 AF083387 AAD21770 AF083388 AAD21771 AF083389 AAD19344 AF083390 AAD19345 AF083391 AAD19346 AF330040 AAK00344 AI339675 AI695058 AJ007042 CAB45386 AK026939 AK289697 BAF82386 AY694128 AAU09264 BC020545 AAH20545 BC032731 BC052254 AAH52254 BC070176 AAH70176 BC094825 AAH94825 BC110899 BC141815 AAI41816 BC144464 BC152412 AAI52413 BC166668 AAI66668 BM982021 CX866583 DQ185035 XM_005248001 XP_005248058 XM_005248002 XP_005248059 XM_005248005 XP_005248062 XM_006713914 XP_006713977 XM_006713915 XP_006713978 XM_011513557 XP_011511859 XM_011513558 XP_011511860 XM_011513559 XP_011511861 XM_011513560 XP_011511862 NM_001042424 NP_001035889 NM_007331 NP_015627 NM_133330 NP_579877 NM_133331 NP_579878 NM_133334 NP_579889 NM_133335 NP_579890 NM_014919 NM_133332 NM_133333 NM_133336
Function Histone methyltransferase with histone H3 'Lys-27' (H3K27me) methyltransferase activity. Isoform RE-IIBP may act as a transcription regulator that binds DNA and suppresses IL5 transcription through HDAC recruitment. {ECO:0000269|PubMed:11152655, ECO:0000269|PubMed:16115125, ECO:0000269|PubMed:18172012}.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267, ECO:0000269|PubMed:15677557, ECO:0000269|PubMed:16197452}. Chromosome {ECO:0000305}.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:9618163}.
Top Pathways Lysine degradation, Transcriptional misregulation in cancer

Human WHSC1 ELISA Kit - E030846 from Biobool

Category ELISA Kit
Sensitivity 0.156 ng/mL (mean of 6 independent assays).

Human NSD2 ELISA Kit - E091720 from Biobool

Category ELISA Kit

Probable Histone-Lysine N-Methyltransferase NSD2 (WHSC1), ELISA Kit - MBS9393382 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Probable Histone-Lysine N-Methyltransferase NSD2 (WHSC1), ELISA Kit - MBS9393390 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Probable Histone-Lysine N-Methyltransferase NSD2 (WHSC1), ELISA Kit - MBS9393378 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Probable Histone-Lysine N-Methyltransferase NSD2 (WHSC1), ELISA Kit - MBS9393381 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Probable Histone-Lysine N-Methyltransferase NSD2 (WHSC1), ELISA Kit - MBS9393383 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Probable Histone-Lysine N-Methyltransferase NSD2 (WHSC1), ELISA Kit - MBS9393384 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Probable Histone-Lysine N-Methyltransferase NSD2 (WHSC1), ELISA Kit - MBS109280 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 0.1ng/ml.
Range 0.625ng/ml-20ng/ml.
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