EIF4EBP1

Gene Symbol EIF4EBP1
Entrez Gene 1978
Alt Symbol 4E-BP1, 4EBP1, BP-1, PHAS-I
Species Human
Gene Type protein-coding
Description eukaryotic translation initiation factor 4E binding protein 1
Other Description eIF4E-binding protein 1|eukaryotic translation initiation factor 4E-binding protein 1|phosphorylated heat- and acid-stable protein regulated by insulin 1
Swissprots Q6IBN3 Q13541 B2R502 D3DSW8
Accessions CCW44094 EAW63341 EAW63342 Q13541 AB044548 BAB18650 AK312011 BAG34949 BC004459 AAH04459 BC058073 AAH58073 BF964628 BT007162 AAP35826 CR456769 CAG33050 DQ890570 ABM92187 DQ893731 ABM84657 L36055 AAA62269 NM_004095 NP_004086
Function Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways. {ECO:0000269|PubMed:22578813, ECO:0000269|PubMed:7935836}.
Top Pathways RNA transport, Choline metabolism in cancer, AMPK signaling pathway, PI3K-Akt signaling pathway, ErbB signaling pathway

Human-EIF4EBP1-cDNA-Clone - DC01492 from Abgent, a WuXi AppTec company

Prices $159.30
Sizes 10 µg
Species Human
Accession BC004459

EIF4EBP1 - MBS1277863 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC004459

Human EIF4EBP1 ORF Clone(NM_004095.3) - CDCL162176 from Creative Biomart

Species Human
Accession NM_004095.3

4EBP1 - CL01024H01 from Elabscience

Species Human
Accession NM_004095.3

Human 4EBP1 ORF clone(NM_004095.3) - CDCL182505 from Creative biogene

Species Human

Human EIF4EBP1 ORF Clone (BC004459) - CDCS411605 from Creative biogene

Species Human
Accession Q13541

Human 4E-BP1 Gene - orb90644 from Biorbyt

Prices $264.00
Sizes 10 μg
Species Human
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