Gene Symbol |
Mmp3
|
Entrez Gene |
17392
|
Alt Symbol |
SLN-1, SLN1, STR-1, Stmy1, Str1
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
matrix metallopeptidase 3
|
Other Description |
EMS-2|MMP-3|SL-1|matrix metalloproteinase 3|matrix metalloproteinase-3|progelatinase|stromelysin 1|stromelysin-1|transin-1
|
Swissprots |
P28862
|
Accessions |
EDL24935 P28862 AK148467 BAE28570 AY622967 AAT46398 BC006725 AAH06725 X63162 CAA44860 X66402 CAA47029 NM_010809 NP_034939
|
Function |
Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
|
Subcellular Location |
Secreted, extracellular space, extracellular matrix {ECO:0000305}.
|
Top Pathways |
Rheumatoid arthritis, TNF signaling pathway, Transcriptional misregulation in cancer
|