Gene Symbol | Mmp3 |
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Entrez Gene | 17392 |
Alt Symbol | SLN-1, SLN1, STR-1, Stmy1, Str1 |
Species | Mouse |
Gene Type | protein-coding |
Description | matrix metallopeptidase 3 |
Other Description | EMS-2|MMP-3|SL-1|matrix metalloproteinase 3|matrix metalloproteinase-3|progelatinase|stromelysin 1|stromelysin-1|transin-1 |
Swissprots | P28862 |
Accessions | EDL24935 P28862 AK148467 BAE28570 AY622967 AAT46398 BC006725 AAH06725 X63162 CAA44860 X66402 CAA47029 NM_010809 NP_034939 |
Function | Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. |
Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000305}. |
Top Pathways | Rheumatoid arthritis, TNF signaling pathway, Transcriptional misregulation in cancer |
MMP-3 CRISPR/Cas9 KO Plasmid (m) - sc-421676 from Santa Cruz Biotechnology
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MMP-3 HDR Plasmid (m) - sc-421676-HDR from Santa Cruz Biotechnology
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MMP-3 Double Nickase Plasmid (m) - sc-421676-NIC from Santa Cruz Biotechnology
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MMP-3 Double Nickase Plasmid (m2) - sc-421676-NIC-2 from Santa Cruz Biotechnology
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MMP-3 CRISPR Activation Plasmid (m) - sc-421676-ACT from Santa Cruz Biotechnology
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MMP-3 CRISPR Activation Plasmid (m2) - sc-421676-ACT-2 from Santa Cruz Biotechnology
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MMP-3 Lentiviral Activation Particles (m) - sc-421676-LAC from Santa Cruz Biotechnology
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MMP-3 Lentiviral Activation Particles (m2) - sc-421676-LAC-2 from Santa Cruz Biotechnology
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MMP-3 siRNA (m) - sc-37265 from Santa Cruz Biotechnology
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MMP-3 shRNA Plasmid (m) - sc-37265-SH from Santa Cruz Biotechnology
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MMP-3 shRNA (m) Lentiviral Particles - sc-37265-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU031941 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN35659 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND35659 from Sigma-Aldrich
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MMP3 siRNA (Mouse) - CRM2563 from Cohesion Biosciences
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shRNA set against Mouse MMP3 (NM_010809.1) - SHH343100 from Creative biogene
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shRNA set against Mouse Mmp3(NM_010809.1) - SHH194105 from Creative biogene
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Mouse MMP3 siRNA - orb282039 from Biorbyt
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MMP3 shRNA Plasmid (Mouse) - CHM2563 from Cohesion Biosciences
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MMP3 miRNA 3'UTR clone - MiUTR1M-07182 from Creative biogene
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