C5

Gene Symbol	C5
Entrez Gene	727
Alt Symbol	C5D, C5a, C5b, CPAMD4, ECLZB
Species	Human
Gene Type	protein-coding
Description	complement component 5
Other Description	C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4|C5a anaphylatoxin|anaphylatoxin C5a analog|complement C5|prepro-C5
Swissprots	Q27I61 P01031 Q14CJ0
Accessions	AAP13242 ABD48959 BAO02074 EAW87480 P01031 AB209031 BAD92268 AK310774 AK310780 AV682721 BC022299 BC113738 AAI13739 BC113740 AAI13741 BG533927 CB250401 M57729 AAA51925 M65134 AAA51856 S79279 AAB35171 T82068 XM_011518980 XP_011517282 XM_011518981 XP_011517283 XM_011518982 XP_011517284 NM_001735 NP_001726
Function	Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Staphylococcus aureus infection, Pertussis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human C5 / C5a full length protein - ab61918 from Abcam Category Protein Prices $278.00 Sizes 20 µg Source E. coli Species Human

Active human C5 protein fragment - ab167724 from Abcam Category Protein Prices $302.00 Sizes 50 µg Source E. coli Species Human

C5 / C5b peptide - ab46166 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

C5 / C5b peptide - ab46167 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human C5 / C5a full length protein - ab51973 from Abcam Category Protein Prices $273.00 Sizes 20 µg Source E. coli Species Human

Human C5 / C5a peptide - ab92654 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human C5 / C5a protein fragment - ab176089 from Abcam Category Protein Prices $576.00 Sizes 20 µg Source Synthetic Species Human

Human C5 / C5b peptide - ab46169 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human C5 / C5b peptide - ab46170 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human C5 peptide - ab69125 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human C5 protein fragment - ab157988 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human C5 protein fragment - ab176056 from Abcam Category Protein Prices $1,379.00 Sizes 10 µg Source Synthetic Species Human

Mouse C5 / C5a full length protein - ab151847 from Abcam Category Protein Source E. coli Species Mouse

Mouse C5 / C5a protein fragment - ab90896 from Abcam Category Protein Source E. coli Species Mouse

Complement C5 Antibody Blocking Peptide - LS-E9652 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Complement C5 Protein - H00000727-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

C5-Antibody-N-term-Blocking-Peptide - BP8577a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Complement Component C5a - 2037-C5-025 from R&D Systems Category Protein Source E. coli-derived, Thr678-Arg751

Recombinant Human Complement Component C5a, CF - 2037-C5-025/CF from R&D Systems Category Protein Source E. coli-derived, Thr678-Arg751

Complement C5b, 6 complex protein - 32C-CP2031U from Fitzgerald Category Protein Prices $428.80 Sizes 50 µg Species Human

Complement C5 - H00000727-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Complement C5 - H00000727-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Complement C5a - AR31183PU-N from Acris Antibodies Category Protein Prices $235.00 Sizes 20 µg Source E. coli Species Human

Complement C5a - AR31183PU-S from Acris Antibodies Category Protein Prices $135.00 Sizes 5 µg Source E. coli Species Human

Complement C5a Recombinant Protein - 96-070 from ProSci Category Protein Prices $350.00 Sizes 50 µg Source E. coli Species Human

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