JUN

Gene Symbol JUN
Entrez Gene 3725
Alt Symbol AP-1, AP1, c-Jun
Species Human
Gene Type protein-coding
Description jun proto-oncogene
Other Description Jun activation domain binding protein|activator protein 1|enhancer-binding protein AP1|jun oncogene|p39|proto-oncogene c-Jun|transcription factor AP-1|v-jun avian sarcoma virus 17 oncogene homolog|v-jun sarcoma virus 17 oncogene homolog
Swissprots Q6FHM7 Q96G93 P05412
Accessions AAA59197 AAO22993 CAM91157 EAX06628 P05412 BC002646 BC006175 AAH06175 BC009874 AAH09874 BC068522 AAH68522 BG831943 BI793062 BT019759 AAV38564 BU782554 CD370800 CR541724 CAG46525 CR541752 CAG46552 DQ896432 ABM87431 NM_002228 NP_002219
Function Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. {ECO:0000269|PubMed:10995748, ECO:0000269|PubMed:17210646}.
Subcellular Location Nucleus.
Top Pathways TNF signaling pathway, Estrogen signaling pathway, Non-alcoholic fatty liver disease (NAFLD), Oxytocin signaling pathway, Inflammatory bowel disease (IBD)

Phospho-c-Jun (Ser73) (D47G9) XP ® Rabbit mAb (PE Conjugate) - 8752 from Cell Signaling Technology

Prices $329.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone D47G9
Flow cytometric analysis of HeLa cells, λ phosphatase and anisomycin-treated (blue) or anisomycin only-treated (green) using Phospho-c-Jun (Ser73) (D47G9) XP ® Rabbit mAb (PE Conjugate).

Phospho-c-Jun (Ser73) (D47G9) XP ® Rabbit mAb (Alexa Fluor ® 488 Conjugate) - 12714 from Cell Signaling Technology

Prices $329.00
Sizes 100 µl (50 tests)
Host Rabbit
Clonality Monoclonal
Clone D47G9
Flow cytometric analysis of HeLa cells, untreated (blue) or UV-treated (green), using Phospho-c-Jun (Ser73) (D47G9) XP ® Rabbit mAb (Alexa Fluor ® 488 Conjugate).

Phospho-c-Jun (Ser63) (54B3) Rabbit mAb (Biotinylated) - 5464 from Cell Signaling Technology

Prices $299.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone 54B3
Western blot analysis of extracts from C6 cells, untreated or anisomycin-treated, using Phospho-c-Jun (Ser63) (54B3) Rabbit mAb (Biotinylated) and detected with Streptavidin-HRP #3999.

Phospho-c-Jun (Ser73) (D47G9) XP ® Rabbit mAb - 3270 from Cell Signaling Technology

Prices $119.00, $318.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D47G9
Western blot analysis of extracts from NIH/3T3 or C6 cells, untreated or UV-treated, using Phospho-c-Jun (Ser73) (D47G9) XP ® Rabbit mAb (upper) or c-Jun (60A8) Rabbit mAb #9165 (lower).

Phospho-c-Jun (Thr91) Antibody - 2303 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from untreated or UV-treated COS and NIH/3T3 cells, using Phospho-c-Jun (Thr91) Antibody (upper) or c-Jun (60A8) Rabbit mAb #9165 (lower).

Phospho-c-Jun (Ser63) II Antibody - 9261 from Cell Signaling Technology

Prices $287.00, $678.00
Sizes 100 µl (10 western blots), 300 µl (30 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from anisomycin or UV-treated NIH/3T3 cells, using Phospho-c-Jun (Ser63) II Antibody.

Phospho-c-Jun (Thr93) Antibody - 2993 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from Src-3T3 cells, untreated or treated with lambda phosphatase, using Phospho-c-Jun (Thr93) Antibody (upper) or c-Jun (60A8) Rabbit mAb #9165 (lower).

Phospho-c-Jun (Ser73) Antibody - 9164 from Cell Signaling Technology

Prices $287.00, $678.00
Sizes 100 µl (10 western blots), 300 µl (30 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from UV-treated NIH/3T3 cells using Phospho-c-Jun (Ser73) Antibody.

Phospho-c-Jun (Ser243) Antibody - 2994 from Cell Signaling Technology

Prices $287.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from 293 cells, λ phosphatase-treated or UV-treated, using Phospho-c-Jun (Ser243) Antibody (upper) or c-Jun (60A8) Rabbit mAb #9165 (lower).

PhosphoPlus® c-Jun (Ser63) and c-Jun (Ser73) Antibody Kit - 9260 from Cell Signaling Technology

Prices $489.00
Sizes 1 kit (10 western blots)
Clonality Polyclonal

Phospho-c-Jun (Ser63) (54B3) Rabbit mAb - 2361 from Cell Signaling Technology

Prices $109.00, $307.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone 54B3
Western blot analysis of extracts from untreated or anisomycin-treated C6 cells, or untreated or UV-treated 293 cells, using Phospho-c-Jun (Ser63) (54B3) Rabbit mAb (upper) or c-Jun (60A8) Rabbit mAb #9165 (lower).

PathScan ® Multi-Target HCA Stress and Apoptosis Kit - 7103 from Cell Signaling Technology

Prices $689.00
Sizes 1 kit (8 x 140 µl)
Clonality Polyclonal
Signaling pathway for antibodies in the PathScan ® Multi-Target HCA Stress and Apoptosis Kit. Representative confocal immunofluorescent images display typical localization of the individual proteins in untreated (left or top) or treated (right or bottom) cells.

c-Jun (L70B11) Mouse mAb - 2315 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Mouse
Clonality Monoclonal
Clone L70B11
Western blot analysis of extracts from NIH/3T3 and 293 cells, untreated or UV-treated using c-Jun (L70B11) Mouse mAb.

c-Jun (60A8) Rabbit mAb - 9165 from Cell Signaling Technology

Prices $99.00, $246.00, $596.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots), 300 µl (30 western blots)
Host Rabbit
Clonality Monoclonal
Clone 60A8
Western blot analysis of extracts from NIH/3T3 and SK-N-MC cells, untreated or UV-treated, using c-Jun (60A8) Rabbit mAb.

Phospho-c-Jun (Ser73) Antibody - 5170 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

c-Jun Antibody - 9162 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

c-Jun (B-1) - sc-166540 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
c-Jun (B-1): sc-166540. Western blot analysis of c-Jun expression in non-transfected: sc-110760 (A) and human c-Jun transfected: sc-110759 (B) 293 whole cell lysates.

c-Jun (B-2) - sc-376488 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
c-Jun (B-2): sc-376488. Western blot analysis of c-Jun expression in NIH/3T3 whole cell lysates.

c-Jun (D) - sc-44 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Western blot analysis of c-Jun p39 expression in untreated (A,C) and phorbol ester-induced (B,D) NIH/3T3 nuclear extracts. Antibodies tested include c-Jun (D): sc-44 (A,B) and c-Jun (N): sc-45 (C,D).

c-Jun (G-4) - sc-74543 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
c-Jun (G-4): sc-74543. Western blot analysis of c-Jun expression in non-transfected (A) and human c-Jun transfected (B) CHO whole cell lysates.

c-Jun (H-79) - sc-1694 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
c-Jun (H-79): sc-1694. Western blot analysis of c-Jun p39 expression in untreated (A) and phorbol ester-induced (B) NIH/3T3 nuclear extracts.

c-Jun (N) - sc-45 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Western blot analysis of c-Jun p39 expression in untreated (A,C) and phorbol ester-induced (B,D) NIH/3T3 nuclear extracts. Antibodies tested include c-Jun (D): sc-44 (A,B) and c-Jun (N): sc-45 (C,D).

p-c-Jun (C-J 4C4/1) - sc-53182 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
p-c-Jun (C-J 4C4/1): sc-53182. Western blot analysis of c-Jun phosphorylation in non-transfected: sc-117752 (A) and mouse c-Jun transfected: sc-125069 (B) 293T whole cell lysates.

p-c-Jun (KM-1) - sc-822 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
c-Jun (KM-1): sc-822. Immunofluorescence staining of methanol-fixed NIH/3T3 cells showing punctate nuclear staining of phosphorylated c-Jun (A). Immunoperoxidase staining of formalin-fixed, paraffin-embedded human colon carcinoma showing nuclear localization of activated c-Jun (B).

p-c-Jun (Ser 63/73) - sc-16312 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Western blot analysis of human recombinant c-Jun fusion protein (A,C) and human recombinant c-Jun fusion protein phosphorylated by human recombinant JNK1 (B,D). Antibodies tested include p-c-Jun (Ser 63/73)-R: sc-16312-R (A,B) and p-c-Jun (Ser 73)-R: sc-7981-R (C,D).
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