JUN

Gene Symbol JUN
Entrez Gene 3725
Alt Symbol AP-1, AP1, c-Jun
Species Human
Gene Type protein-coding
Description jun proto-oncogene
Other Description Jun activation domain binding protein|activator protein 1|enhancer-binding protein AP1|jun oncogene|p39|proto-oncogene c-Jun|transcription factor AP-1|v-jun avian sarcoma virus 17 oncogene homolog|v-jun sarcoma virus 17 oncogene homolog
Swissprots Q6FHM7 Q96G93 P05412
Accessions AAA59197 AAO22993 CAM91157 EAX06628 P05412 BC002646 BC006175 AAH06175 BC009874 AAH09874 BC068522 AAH68522 BG831943 BI793062 BT019759 AAV38564 BU782554 CD370800 CR541724 CAG46525 CR541752 CAG46552 DQ896432 ABM87431 NM_002228 NP_002219
Function Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. {ECO:0000269|PubMed:10995748, ECO:0000269|PubMed:17210646}.
Subcellular Location Nucleus.
Top Pathways TNF signaling pathway, Estrogen signaling pathway, Non-alcoholic fatty liver disease (NAFLD), Oxytocin signaling pathway, Inflammatory bowel disease (IBD)

SignalSilence ® c-Jun siRNA I - 6203 from Cell Signaling Technology

Category siRNA
Prices $256.00
Sizes 300 µl (3 nmol)
Species Reactivities Human
Western blot analysis of extracts from HeLa cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® c-Jun siRNA I (+) or SignalSilence ® c-Jun siRNA II #6204 (+), using c-Jun (60A8) Rabbit mAb #9165 and α-Tubulin (11H10) Rabbit mAb #2125. The c-Jun (60A8) Rabbit mAb confirms silencing of c-Jun expression, while the α-Tubulin (11H10) Rabbit mAb is used to control for loading and specificity of c-Jun siRNA.

SignalSilence ® c-Jun siRNA II - 6204 from Cell Signaling Technology

Category siRNA
Prices $256.00
Sizes 300 µl (3 nmol)
Species Reactivities Human
Western blot analysis of extracts from HeLa cells, transfected with 100 nM SignalSilence ® Control siRNA (Unconjugated) #6568 (-), SignalSilence ® c-Jun siRNA I #6203 (+) or SignalSilence ® c-Jun siRNA II (+), using c-Jun (60A8) Rabbit mAb #9165 and α-Tubulin (11H10) Rabbit mAb #2125. The c-Jun (60A8) Rabbit mAb confirms silencing of c-Jun expression, while the α-Tubulin (11H10) Rabbit mAb is used to control for loading and specificity of c-Jun siRNA.

c-Jun CRISPR/Cas9 KO Plasmid (h) - sc-400077 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Jun HDR Plasmid (h) - sc-400077-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Jun Double Nickase Plasmid (h) - sc-400077-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Jun Double Nickase Plasmid (h2) - sc-400077-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Jun CRISPR Activation Plasmid (h) - sc-400077-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Jun CRISPR Activation Plasmid (h2) - sc-400077-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Jun Lentiviral Activation Particles (h) - sc-400077-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Jun Lentiviral Activation Particles (h2) - sc-400077-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Jun siRNA (h) - sc-29223 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

c-Jun shRNA Plasmid (h) - sc-29223-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

c-Jun shRNA (h) Lentiviral Particles - sc-29223-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

c-Jun siRNA (h2) - sc-44201 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

c-Jun shRNA Plasmid (h2) - sc-44201-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

c-Jun shRNA (h2) Lentiviral Particles - sc-44201-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

c-Jun siRNA (chicken) - sc-270090 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Bird

c-Jun shRNA Plasmid (chicken) - sc-270090-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Bird

c-jun RNAi - H00003725-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN1032 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1032 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

JUN siRNA (Human) - CRH2506 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

c-Jun CRISPR/Cas9 KO Plasmid (h2) - sc-400077-KO-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

c-Jun HDR Plasmid (h2) - sc-400077-HDR-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JUN, siRNA - MBS8227968 from MyBioSource

Category siRNA
Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human
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