| Gene Symbol | UGT8 |
|---|---|
| Entrez Gene | 7368 |
| Alt Symbol | CGT, UGT4 |
| Species | Human |
| Gene Type | protein-coding |
| Description | UDP glycosyltransferase 8 |
| Other Description | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase|UDP-galactose ceramide galactosyltransferase|UDP-galactose-ceramide galactosyltransferase|ceramide UDP-galactosyltransferase|cerebroside synthase|uridine diphosphate glycosyltransferase 8 |
| Swissprots | Q16880 O00196 B3KXU7 |
| Accessions | AAC50815 EAX06307 Q16880 AK127970 BAG54609 AK225763 AK294438 BAG57681 AL137342 BC075069 AAH75069 DA140992 DA295156 U30930 AAC50565 U62899 AAC51187 XM_006714302 XP_006714365 XM_006714303 XP_006714366 XM_011532232 XP_011530534 NM_001128174 NP_001121646 NM_003360 NP_003351 |
| Function | Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. |
| Subcellular Location | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Top Pathways | Ether lipid metabolism, Sphingolipid metabolism |