| Gene Symbol |
UGT8
|
| Entrez Gene |
7368
|
| Alt Symbol |
CGT, UGT4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
UDP glycosyltransferase 8
|
| Other Description |
2-hydroxyacylsphingosine 1-beta-galactosyltransferase|UDP-galactose ceramide galactosyltransferase|UDP-galactose-ceramide galactosyltransferase|ceramide UDP-galactosyltransferase|cerebroside synthase|uridine diphosphate glycosyltransferase 8
|
| Swissprots |
Q16880 O00196 B3KXU7
|
| Accessions |
AAC50815 EAX06307 Q16880 AK127970 BAG54609 AK225763 AK294438 BAG57681 AL137342 BC075069 AAH75069 DA140992 DA295156 U30930 AAC50565 U62899 AAC51187 XM_006714302 XP_006714365 XM_006714303 XP_006714366 XM_011532232 XP_011530534 NM_001128174 NP_001121646 NM_003360 NP_003351
|
| Function |
Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system.
|
| Subcellular Location |
Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
|
| Top Pathways |
Ether lipid metabolism, Sphingolipid metabolism
|