Gene Symbol | UGT8 |
---|---|
Entrez Gene | 7368 |
Alt Symbol | CGT, UGT4 |
Species | Human |
Gene Type | protein-coding |
Description | UDP glycosyltransferase 8 |
Other Description | 2-hydroxyacylsphingosine 1-beta-galactosyltransferase|UDP-galactose ceramide galactosyltransferase|UDP-galactose-ceramide galactosyltransferase|ceramide UDP-galactosyltransferase|cerebroside synthase|uridine diphosphate glycosyltransferase 8 |
Swissprots | Q16880 O00196 B3KXU7 |
Accessions | AAC50815 EAX06307 Q16880 AK127970 BAG54609 AK225763 AK294438 BAG57681 AL137342 BC075069 AAH75069 DA140992 DA295156 U30930 AAC50565 U62899 AAC51187 XM_006714302 XP_006714365 XM_006714303 XP_006714366 XM_011532232 XP_011530534 NM_001128174 NP_001121646 NM_003360 NP_003351 |
Function | Catalyzes the transfer of galactose to ceramide, a key enzymatic step in the biosynthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Top Pathways | Ether lipid metabolism, Sphingolipid metabolism |
UGT8 CRISPR/Cas9 KO Plasmid (h) - sc-405110 from Santa Cruz Biotechnology
|
||||||||
UGT8 HDR Plasmid (h) - sc-405110-HDR from Santa Cruz Biotechnology
|
||||||||
UGT8 Double Nickase Plasmid (h) - sc-405110-NIC from Santa Cruz Biotechnology
|
||||||||
UGT8 Double Nickase Plasmid (h2) - sc-405110-NIC-2 from Santa Cruz Biotechnology
|
||||||||
UGT8 CRISPR Activation Plasmid (h) - sc-405110-ACT from Santa Cruz Biotechnology
|
||||||||
UGT8 CRISPR Activation Plasmid (h2) - sc-405110-ACT-2 from Santa Cruz Biotechnology
|
||||||||
UGT8 Lentiviral Activation Particles (h) - sc-405110-LAC from Santa Cruz Biotechnology
|
||||||||
UGT8 Lentiviral Activation Particles (h2) - sc-405110-LAC-2 from Santa Cruz Biotechnology
|
||||||||
UGT8 siRNA (h) - sc-89005 from Santa Cruz Biotechnology
|
||||||||
UGT8 shRNA Plasmid (h) - sc-89005-SH from Santa Cruz Biotechnology
|
||||||||
UGT8 shRNA (h) Lentiviral Particles - sc-89005-V from Santa Cruz Biotechnology
|
||||||||
UGT8 RNAi - H00007368-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU019091 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN22476 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22476 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR02603 from Sigma-Aldrich
|
||||||||
UGT8 siRNA (Human) - CRH5039 from Cohesion Biosciences
|
||||||||
UGT8 - MBS8237959 from MyBioSource
|
||||||||
shRNA set against Human UGT8 (NM_003360.3) - SHH440272 from Creative biogene
|
||||||||
UGT8 shRNA Plasmid (Human) - CHH5039 from Cohesion Biosciences
|
||||||||
UGT8 miRNA 3'UTR clone - MiUTR3H-04040 from Creative biogene
|
||||||||
UGT8 miRNA 3'UTR clone - MiUTR3H-04041 from Creative biogene
|