Id2

Gene Symbol Id2
Entrez Gene 15902
Alt Symbol AI255428, C78922, Idb2, bHLHb26
Species Mouse
Gene Type protein-coding
Description inhibitor of DNA binding 2
Other Description DNA-binding protein inhibitor ID-2|inhibitor of differentiation 2
Swissprots P41136 O88604
Accessions AAD05214 EDL36979 P41136 AK003222 BAB22651 AK013239 AK013378 AK135547 BAE22577 AK146346 BAE27099 AK146606 BAE27298 BC006921 AAH06921 BC053699 AAH53699 BQ044638 M69293 AAA79771 NM_010496 NP_034626
Function Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle and cardiac myocyte differentiation. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Restricts the CLOCK and ARNTL/BMAL1 localization to the cytoplasm. Plays a role in both the input and output pathways of the circadian clock: in the input component, is involved in modulating the magnitude of photic entrainment and in the output component, contributes to the regulation of a variety of liver clock-controlled genes involved in lipid metabolism. {ECO:0000269|PubMed:16556596, ECO:0000269|PubMed:192
Subcellular Location Cytoplasm. Nucleus.
Top Pathways TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer

Recombinant Mouse DNA-binding protein inhibitor ID-2(Id2) - CSB-YP010967MO CSB-EP010967MO CSB-BP010967MO CSB-MP010967MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Recombinant Mouse ID2 Protein - ID2-7980M from Creative Biomart

Category Protein
Source Mammalian Cells
Species Mouse

DNA-binding protein inhibitor ID-2 (Id2), Recombinant Protein - MBS954517 from MyBioSource

Category Protein
Prices $870.00, $870.00, $1,095.00, $1,095.00, $1,270.00, $1,270.00, $1,725.00, $1,725.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse
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