Gene Symbol | Slc27a1 |
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Entrez Gene | 94172 |
Alt Symbol | FATP |
Species | Rat |
Gene Type | protein-coding |
Description | solute carrier family 27 (fatty acid transporter), member 1 |
Other Description | FATP-1|fatty acid transport protein 1|long-chain fatty acid transport protein 1|solute carrier family 27 member 1|solute carrier family 27, member 1 |
Swissprots | P97849 |
Accessions | EDL90773 EDL90774 EDL90775 EDL90776 P97849 BC074014 AAH74014 U89529 AAC53424 XM_006252953 XP_006253015 XM_006252954 XP_006253016 XM_008771156 XP_008769378 XM_008771157 XP_008769379 NM_053580 NP_446032 |
Function | Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of Fatp1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. May act directly as a bona fide transporter, or alternatively, in a cytoplasmic or membrane- associated multimeric protein complex to trap and draw fatty acids towards accumulation. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:15848183}; Single-pass membrane protein {ECO:0000269|PubMed:15848183}. Endomembrane system {ECO:0000269|PubMed:15848183}; Single-pass membrane protein {ECO:0000269|PubMed:15848183}. Cytoplasm {ECO:0000269|PubMed:15848183}. Note=Plasma membrane and intracellular membranes, at least in adipocytes. Predominantly cytoplasmic in myocytes. |
Top Pathways | PPAR signaling pathway |
Fatty Acid Transport Protein 1 (FATP1), Rat, ELISA Kit - SEG555Ra from ARP American Research Products
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Long-chain fatty acid transport protein 1, Slc27a1, Rat, ELISA Kit - E12692r from ARP American Research Products
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ELISA Kit for Fatty Acid Transport Protein 1 (FATP1) - SEG555Ra from Cloud-clone
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Slc27a1 - EKR0980 from Nordic BioSite
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Slc27a1 - EKR980 from Nordic BioSite
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Rat Slc27a1 ELISA Kit - E096911 from Biobool
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SLC27A1 ELISA Kit (Rat) (OKEH03620) - OKEH03620 from Aviva Systems Biology
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Rat Long-chain fatty acid transport protein 1 ELISA Kit - EK3101 from Signalway Antibody
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Rat Long-chain fatty acid transport protein 1 (SLC27A1) ELISA Kit - AE18838RA from ARP American Research Products
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Fatty Acid Transport Protein 1 (FATP1), ELISA Kit - MBS456338 from MyBioSource
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Long-chain fatty acid transport protein 1, ELISA Kit - MBS9426935 from MyBioSource
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