ARG2

Gene Symbol ARG2
Entrez Gene 384
Alt Symbol -
Species Human
Gene Type protein-coding
Description arginase 2
Other Description L-arginine amidinohydrolase|L-arginine ureahydrolase|arginase, type II|arginase-2, mitochondrial|kidney arginase|kidney-type arginase|non-hepatic arginase|nonhepatic arginase|type II arginase
Swissprots Q6FHY8 P78540 B2R690
Accessions CBX47614 EAW80943 EAW80944 P78540 AK312484 BAG35387 AL135439 AY074489 AAL71548 BC001350 AAH01350 BC008464 AAH08464 BC029050 AAH29050 CR536550 CAG38787 D86724 BAA13158 U75667 AAB39855 U82256 AAC51664 NM_001172 NP_001163
Function May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders. {ECO:0000269|PubMed:12859189}.
Subcellular Location Mitochondrion.
Tissue Specificity Expressed most strongly in kidney and prostate, much less strongly in the brain, skeletal muscle, placenta, lung, mammary gland, macrophage, uterus, testis and gut, but apparently not in the liver, heart and pancreas.
Top Pathways Amoebiasis, Arginine and proline metabolism, Biosynthesis of amino acids

ARG2-Over-expression-Lysate - LY12328a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag ARG2 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ARG2 gene

Arginase-2 Lysate(Denatured) - H00000384-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

ARG2 293 Cell Lysate - 409408 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

ARG2 Overexpression Lysate (Denatured) - H00000384-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

ARG2 Overexpression Lysate (Native) - NBL1-07663 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: ARG2 Overexpression Lysate (Adult Normal) [NBL1-07663] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ARG2.

arginase II (h): 293T Lysate - sc-114274 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

ARG2 Over-expression Lysate Product - GWB-87328C from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human ARG2 Knockdown Stable Cell Line - CSC-DC000842 from Creative biogene

Category Cell Line
Species Human
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