ARG2

Gene Symbol	ARG2
Entrez Gene	384
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	arginase 2
Other Description	L-arginine amidinohydrolase|L-arginine ureahydrolase|arginase, type II|arginase-2, mitochondrial|kidney arginase|kidney-type arginase|non-hepatic arginase|nonhepatic arginase|type II arginase
Swissprots	Q6FHY8 P78540 B2R690
Accessions	CBX47614 EAW80943 EAW80944 P78540 AK312484 BAG35387 AL135439 AY074489 AAL71548 BC001350 AAH01350 BC008464 AAH08464 BC029050 AAH29050 CR536550 CAG38787 D86724 BAA13158 U75667 AAB39855 U82256 AAC51664 NM_001172 NP_001163
Function	May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders. {ECO:0000269|PubMed:12859189}.
Subcellular Location	Mitochondrion.
Tissue Specificity	Expressed most strongly in kidney and prostate, much less strongly in the brain, skeletal muscle, placenta, lung, mammary gland, macrophage, uterus, testis and gut, but apparently not in the liver, heart and pancreas.
Top Pathways	Amoebiasis, Arginine and proline metabolism, Biosynthesis of amino acids

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

arginase II CRISPR/Cas9 KO Plasmid (h) - sc-400639 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

arginase II HDR Plasmid (h) - sc-400639-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

arginase II Double Nickase Plasmid (h) - sc-400639-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

arginase II Double Nickase Plasmid (h2) - sc-400639-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

arginase II CRISPR Activation Plasmid (h) - sc-400639-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

arginase II CRISPR Activation Plasmid (h2) - sc-400639-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

arginase II Lentiviral Activation Particles (h) - sc-400639-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

arginase II Lentiviral Activation Particles (h2) - sc-400639-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

arginase II siRNA (h) - sc-29729 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

arginase II shRNA Plasmid (h) - sc-29729-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

arginase II shRNA (h) Lentiviral Particles - sc-29729-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ARG2 RNAi - H00000384-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU046951 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1370 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit - CKOZFN1216 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1216 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1370 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07264 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr07264

ARG2 siRNA (Human) - CRH0275 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ARG2 - MBS8216998 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

arginase II CRISPR/Cas9 KO Plasmid (h2) - sc-400639-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

arginase II HDR Plasmid (h2) - sc-400639-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

shRNA set against Human ARG2(NM_001172.3) - SHG068923 from Creative biogene Category siRNA Species Reactivities Human

Human ARG2 siRNA - orb260777 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ARG2 shRNA Plasmid (Human) - CHH0275 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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