CYP2B6

Gene Symbol CYP2B6
Entrez Gene 1555
Alt Symbol CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450
Species Human
Gene Type protein-coding
Description cytochrome P450, family 2, subfamily B, polypeptide 6
Other Description 1,4-cineole 2-exo-monooxygenase|cytochrome P450 2B6|cytochrome P450 IIB1|cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6
Swissprots P20813 Q9UK46 Q2V565 B4DWP3
Accessions AAD25924 AAF32444 ABB84469 AEA03268 AEA03269 AEA03270 AEA03271 AEA03272 AEA03273 AEA03274 AEA03275 AEA03276 AEA03277 EAW57015 P20813 AF182277 AAF13602 AK301620 BAG63105 BC067430 AAH67430 BC067431 AAH67431 M29874 AAA52144 X06399 X06400 X13494 XM_005258569 XP_005258626 XM_006723050 XP_006723113 XM_011526546 XP_011524848 XM_011526547 XP_011524849 XM_011526548 XP_011524850 XM_011526549 XP_011524851 XM_011526550 XP_011524852 NM_000767 NP_000758
Function Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,4-cineole 2-exo-monooxygenase. {ECO:0000269|PubMed:11695850, ECO:0000269|PubMed:20061448, ECO:0000269|PubMed:21875942, ECO:0000269|PubMed:22909231}.
Subcellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue Specificity Expressed in liver, lung and heart right ventricle. {ECO:0000269|PubMed:10768437}.
Top Pathways Arachidonic acid metabolism, Retinol metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450

CYP2B6 (H-110) - sc-67224 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CYP2B6 (H-110): sc-67224. Western blot analysis of CYP2B6 expression in A549 whole cell lysate.

CYP2B6 (N-18) - sc-55926 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CYP2B6 (Y-17) - sc-55927 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CYP2B6 (C-15) - sc-55924 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Cytochrome P450 2B6 antibody - ab69652 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Cytochrome P450 2B6 antibody (ab69652) at 1/500 dilutionLane 1 : Extracts from HT-29 cellsLane 2 : Extracts from HT-29 cells with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-Cytochrome P450 2B6 antibody - ab22734 from Abcam

Prices $370.00
Sizes 50 µl
Host Sheep
Clonality Polyclonal

Anti-Cytochrome P450 2B6 antibody - ab198870 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Cytochrome P450 2B6 antibody (ab198870) at 1/400 dilution + Human colon cancer tissue lysate at 40 µg

Anti-Cytochrome P450 2B6 antibody [EPR9985(B)] - ab140609 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9985(B)
All lanes : Anti-Cytochrome P450 2B6 antibody [EPR9985(B)] (ab140609) at 1/1000 dilutionLane 1 : HepG2 cell lysateLane 2 : Fetal kidney lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit IgG at 1/2000 dilution

Anti-CYP2B6 Antibody (clone 3D5) - LS-C337636 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 3D5
IHC of paraffin-embedded Carcinoma of Human bladder tissue using anti-CYP2B6 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-CYP2B6 Antibody (aa215-264) IHC-plus™ - LS-B8085 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-CYP2B6 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8085 dilution 5-7.5 ug/ml.

Anti-CYP2B6 Antibody (aa 235-263) IHC-plus™ - LS-B10481 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-CYP2B6 antibody IHC staining of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-CYP2B6 Antibody (His271) - LS-C192025 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP2B6 Antibody (aa242-270, AP) - LS-C208759 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP2B6 Antibody (aa242-270, APC) - LS-C208760 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP2B6 Antibody (aa242-270, Biotin) - LS-C208761 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP2B6 Antibody (aa242-270, FITC) - LS-C208762 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP2B6 Antibody (aa242-270, Azide-free, HRP) - LS-C208763 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP2B6 Antibody (aa242-270, PE) - LS-C208764 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP2B6 Antibody (aa242-270) - LS-C320716 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP2B6 Antibody (aa241-290) IHC-plus™ - LS-B9249 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-CYP2B6 antibody IHC staining of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Cytochrome P450 2B6 Antibody (3D5) - NBP2-01800 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3D5

Cytochrome P450 2B6 Antibody - NBP1-57978 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

Cytochrome P450 2B6 Antibody - NBP2-13894 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Cytochrome P450 2B6 Antibody [NBP2-13894] Staining of human liver shows strong cytoplasmic and nuclear positivity in hepatocytes.

Cytochrome P450 Polyclonal Antibody - bs-2352R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-Cytochrome P450 2B6 antibody produced in rabbit - SAB4500588 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-Cytochrome P450 2B6: <B>Cat. No. SAB4500588</B>: Immunoblotting analysis of extracts from HT-29 cells, using Anti-Cytochrome P450 2B6 antibody. The lane on the left was treated with the Anti-Cytochrome P450 2B6 antibody. The lane on the right (negative control) was treated with both Anti-Cytochrome P450 2B6 antibody and the synthesized immunogen peptide.
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