CYP2B6

Gene Symbol CYP2B6
Entrez Gene 1555
Alt Symbol CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450
Species Human
Gene Type protein-coding
Description cytochrome P450, family 2, subfamily B, polypeptide 6
Other Description 1,4-cineole 2-exo-monooxygenase|cytochrome P450 2B6|cytochrome P450 IIB1|cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6
Swissprots P20813 Q9UK46 Q2V565 B4DWP3
Accessions AAD25924 AAF32444 ABB84469 AEA03268 AEA03269 AEA03270 AEA03271 AEA03272 AEA03273 AEA03274 AEA03275 AEA03276 AEA03277 EAW57015 P20813 AF182277 AAF13602 AK301620 BAG63105 BC067430 AAH67430 BC067431 AAH67431 M29874 AAA52144 X06399 X06400 X13494 XM_005258569 XP_005258626 XM_006723050 XP_006723113 XM_011526546 XP_011524848 XM_011526547 XP_011524849 XM_011526548 XP_011524850 XM_011526549 XP_011524851 XM_011526550 XP_011524852 NM_000767 NP_000758
Function Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,4-cineole 2-exo-monooxygenase. {ECO:0000269|PubMed:11695850, ECO:0000269|PubMed:20061448, ECO:0000269|PubMed:21875942, ECO:0000269|PubMed:22909231}.
Subcellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue Specificity Expressed in liver, lung and heart right ventricle. {ECO:0000269|PubMed:10768437}.
Top Pathways Arachidonic acid metabolism, Retinol metabolism, Metabolism of xenobiotics by cytochrome P450, Drug metabolism - cytochrome P450

CYP2B6 overexpression lysate - LY400259 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

Cytochrome P450 2B6 Overexpression Lysate (Native) - NBP2-04177 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Cytochrome P450 2B6 Overexpression Lysate (Adult Normal) [NBP2-04177] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Cytochrome P450 2B6.

Panoply™ Human CYP2B6 Knockdown Stable Cell Line - CSC-DC003955 from Creative biogene

Category Cell Line
Species Human
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