| Gene Symbol |
Ctsk
|
| Entrez Gene |
13038
|
| Alt Symbol |
AI323530, MMS10-Q, Ms10q, catK
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
cathepsin K
|
| Other Description |
Cat K|minisatellite 10q detected by probe MMS10
|
| Swissprots |
O88718 P55097
|
| Accessions |
CAA06825 EDL38817 EDL38818 P55097 AK003425 BAB22783 AK132648 BAE21279 BC046320 AAH46320 D18958 X94444 CAA64218 XM_006500974 XP_006501037 NM_007802 NP_031828
|
| Function |
Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Lysosome {ECO:0000250}.
|
| Top Pathways |
Toll-like receptor signaling pathway, Lysosome, Osteoclast differentiation, Rheumatoid arthritis
|