Gene Symbol | Ctsk |
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Entrez Gene | 13038 |
Alt Symbol | AI323530, MMS10-Q, Ms10q, catK |
Species | Mouse |
Gene Type | protein-coding |
Description | cathepsin K |
Other Description | Cat K|minisatellite 10q detected by probe MMS10 |
Swissprots | O88718 P55097 |
Accessions | CAA06825 EDL38817 EDL38818 P55097 AK003425 BAB22783 AK132648 BAE21279 BC046320 AAH46320 D18958 X94444 CAA64218 XM_006500974 XP_006501037 NM_007802 NP_031828 |
Function | Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation (By similarity). {ECO:0000250}. |
Subcellular Location | Lysosome {ECO:0000250}. |
Top Pathways | Toll-like receptor signaling pathway, Lysosome, Osteoclast differentiation, Rheumatoid arthritis |
cathepsin K CRISPR/Cas9 KO Plasmid (m) - sc-419879 from Santa Cruz Biotechnology
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cathepsin K HDR Plasmid (m) - sc-419879-HDR from Santa Cruz Biotechnology
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cathepsin K Double Nickase Plasmid (m) - sc-419879-NIC from Santa Cruz Biotechnology
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cathepsin K Double Nickase Plasmid (m2) - sc-419879-NIC-2 from Santa Cruz Biotechnology
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cathepsin K CRISPR Activation Plasmid (m) - sc-419879-ACT from Santa Cruz Biotechnology
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cathepsin K CRISPR Activation Plasmid (m2) - sc-419879-ACT-2 from Santa Cruz Biotechnology
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cathepsin K Lentiviral Activation Particles (m) - sc-419879-LAC from Santa Cruz Biotechnology
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cathepsin K Lentiviral Activation Particles (m2) - sc-419879-LAC-2 from Santa Cruz Biotechnology
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cathepsin K siRNA (m) - sc-29937 from Santa Cruz Biotechnology
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cathepsin K shRNA Plasmid (m) - sc-29937-SH from Santa Cruz Biotechnology
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cathepsin K shRNA (m) Lentiviral Particles - sc-29937-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU021151 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN29391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND29391 from Sigma-Aldrich
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CTSK siRNA (Mouse) - CRM0909 from Cohesion Biosciences
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CTSK - MBS8231954 from MyBioSource
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shRNA set against Mouse CTSK (NM_007802.3) - SHH271585 from Creative biogene
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shRNA set against Mouse Ctsk(NM_007802.3) - SHG206723 from Creative biogene
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Mouse CTSK siRNA - orb280385 from Biorbyt
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CTSK shRNA Plasmid (Mouse) - CHM0909 from Cohesion Biosciences
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CTSK miRNA 3'UTR clone - MiUTR1M-03447 from Creative biogene
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