COL4A3

Gene Symbol	COL4A3
Entrez Gene	1285
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	collagen, type IV, alpha 3 (Goodpasture antigen)
Other Description	collagen IV, alpha-3 polypeptide|collagen alpha-3(IV) chain|tumstatin
Swissprots	Q9UDJ9 Q01955 Q53RW8 Q9UDL0 Q9UDK9 Q9NYC4 Q53QQ1 Q53R14 Q9BQT2 Q9UDL1
Accessions	AAA52044 AAF63713 AAX93111 AAY14671 AAY24251 BAA25064 CAC36101 EAW70848 EAW70849 EAW70850 EAW70851 EAW70852 EAW70853 EAW70854 EAW70855 EAW70856 EAW70857 Q01955 AF258351 AAF72632 AU099354 BC156138 AAI56139 BM670570 BM712932 CD675393 EU268882 ABX71213 M81379 AAA51556 M92993 AAA21610 S55790 AAB19637 U02519 AAA18942 U02520 AAA18943 X80031 CAA56335 XM_005246276 XP_005246333 XM_005246277 XP_005246334 XM_005246280 XP_005246337 XM_006712245 XP_006712308 XM_011510555 XP_011508857 XM_011510556 XP_011508858 XR_241280 NM_000091 NP_000082 NM_031362 NM_031363 NM_031364 NM_031365 NM_031366
Function	Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
Subcellular Location	Secreted, extracellular space, extracellular matrix, basement membrane. Note=Colocalizes with COL4A4 and COL4A5 in GBM, tubular basement membrane (TBM) and synaptic basal lamina (BL). {ECO:0000250}.
Tissue Specificity	Alpha 3 and alpha 4 type IV collagens are colocalized and present in kidney, eye, basement membranes of lens capsule, cochlea, lung, skeletal muscle, aorta, synaptic fibers, fetal kidney and fetal lung. PubMed:8083201 reports similar levels of expression of alpha 3 and alpha 4 type IV collagens in kidney, but PubMed:7523402 reports that in kidney levels of alpha 3 type IV collagen are significantly lower than those of alpha 4 type IV collagen. According to PubMed:8083201, alpha 3 type IV collagen is not detected in heart, brain, placenta, liver, pancreas, extrasynaptic muscle fibers, endoneurial and perineurial nerves, fetal brain, fetal heart and fetal liver. According to PubMed:7523402, alpha 3 type IV collagen is strongly expressed in pancreas, neuroretina and calvaria and not expressed in adrenal, ileum and skin. Isoform 1 and isoform 3 are strongly expressed in kidney, lung, suprarenal capsule, muscle and spleen, in each of these tissues isoform 1 is more abundant than isoform 3.
Top Pathways	Focal adhesion, ECM-receptor interaction, Small cell lung cancer, Amoebiasis, Protein digestion and absorption

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

Human COL4A3 / Tumstatin ELISA Kit (Sandwich ELISA) - LS-F7201 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 1.56 ng/ml Range 1.56-100 ng/ml

Human COL4a3 ELISA Kit - abx151118 from Abbexa Category ELISA Kit Sensitivity 0.56 ng/ml Range 1.563 ng/ml - 100 ng/ml

Collagen alpha-3 (IV) chain (COL4A3), Human, ELISA Kit - CSB-EL005743HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 0.039 ng/ml Range 0.156 ng/ml-10 ng/ml

Collagen Type IV Alpha 3 (COL4a3), Human, ELISA Kit - SEC143Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.113ng/mL Range 0.312-20ng/mL

Collagen Type IV Alpha 3 (COL4a3), ELISA Kit - MBS2022623 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.55ng/mL. Range 1.56-100ng/mL

collagen, type IV, alpha 3 (Goodpasture antigen) , ELISA Kit - MBS919808 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.039 ng/ml. Range 0.156 ng/ml -10 ng/ml.

ELISA Kit for Collagen Type IV Alpha 3 (COL4a3) - SEC143Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.55ng/mL. Range 1.56-100ng/mL The standard curve concentrations used for the ELISA’s were 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.13ng/mL, 1.56ng/mL

Human Collagen alpha-3(IV) chain (COL4A3) ELISA kit - CSB-EL005743HU from Cusabio Category ELISA Kit Sensitivity 0.039 ng/ml Range 0.156 ng/ml-10 ng/ml

ELISA Kit for Collagen Type IV Alpha 3 (COL4a3) - SEC143Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.55ng/mL. Range 1.563-100ng/mL The standard curve concentrations used for the ELISA's were 100ng/mL, 50ng/mL, 25ng/mL, 12.5ng/mL, 6.25ng/mL, 3.125ng/mL, 1.563ng/mL

Collagen Type IV Alpha 3 (COL4a3), Human, ELISA Kit - DL-COL4a3-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

Human COL4a3 ELISA Kit - abx572513 from Abbexa Category ELISA Kit Sensitivity 0.113 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human COL4A3 ELISA Kit - E079335 from Biobool Category ELISA Kit

COL4A3 ELISA Kit (Human) (OKCD00679) - OKCD00679 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.55 ng/mL Range 1.56-100 ng/mL

Collagen Type IV Alpha 3 (COL4a3), ELISA Kit - MBS453214 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.113ng/mL Range 0.312-20ng/mL

Collagen Type IV Alpha 3 (COL4A3), ELISA Kit - MBS9377292 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Collagen IV ELISA Kit - orb405761 from Biorbyt Category ELISA Kit Sensitivity 0.039 ng/ml Range 0.156 ng/ml-10 ng/ml

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