Pdcd1lg2

Gene Symbol Pdcd1lg2
Entrez Gene 58205
Alt Symbol B7-DC, Btdc, F730015O22Rik, PD-L2
Species Mouse
Gene Type protein-coding
Description programmed cell death 1 ligand 2
Other Description PD-1 ligand 2|PDCD1 ligand 2|butyrophilin B7-DC|butyrophilin-like protein|programmed death ligand 2
Swissprots Q9WUL5
Accessions EDL41682 EDL41683 Q9WUL5 AF142780 AAD33892 AK041369 AK089369 BAC40858 AK141111 BAE24564 AK155002 BAE32986 BC104138 AAI04139 BC104139 AAI04140 BY749628 XM_011247309 XP_011245611 NM_021396 NP_067371
Function Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. {ECO:0000269|PubMed:11224527, ECO:0000269|PubMed:11283156, ECO:0000269|PubMed:12719480}.
Subcellular Location Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity Expressed in immature and mature bone marrow- derived dendritic cells and splenic dendritic cells. Highly expressed in placenta, liver and weakly expressed in heart, spleen, lymph nodes and thymus. Also expressed in some tumor cell lines of lymphoid origin. {ECO:0000269|PubMed:11224527, ECO:0000269|PubMed:11283156}.
Top Pathways Cell adhesion molecules (CAMs)

Pdcd-1L2 (P-20) - sc-19100 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Pdcd-1L2 (TY25) - sc-57398 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
Pdcd-1L2 (TY25): sc-57398. Western blot analysis of mouse recombinant Pdcd-1L2 fusion protein.

Anti-B7 DC antibody [TY25] - ab21107 from Abcam

Prices $378.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone TY25

Anti-B7 DC antibody [TY25] - ab21239 from Abcam

Prices $373.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone TY25

Anti-B7 DC antibody [TY25] (FITC) - ab59872 from Abcam

Prices $370.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone TY25

Anti-B7 DC antibody [TY25] (Phycoerythrin) - ab93589 from Abcam

Prices $382.00
Sizes 50 µg
Host Rat
Clonality Monoclonal
Clone TY25
Staining of non-transfected (left) and mouse B7 DC transfected (right) cells with 0.25µg PE Rat IgG2a isotype control (open histogram) or 0.06µg ab93589 (colored histogram). Total viable cells were used for analysis.

Anti-B7 DC antibody [TY25] - Low endotoxin, Azide free - ab171259 from Abcam

Prices $376.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone TY25
Flow cytometric analysis of mouse B7 DC-transfected L5178Y cells labeling B7 DC with 0.125 µg ab171259 (filled histogram) with 0.25 µg Rat IgG2a Isotype Control (open histogram) followed by anti-Rat IgG biotin and streptavidin PE. Total viable cells were used for analysis.

PD-L2/B7-DC/PDCD1LG2 Antibody - AF1022 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal

PD-L2/B7-DC/PDCD1LG2 Antibody (168633) [Unconjugated] - MAB1022 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Rat
Clonality Monoclonal
Clone 168633
HEK293 human embryonic kidney cell line transfected with either mouse PD-L2/B7-DC (filled histogram) or irrelevant transfectants (open histogram) was stained with Rat Anti-Mouse PD‑L2/B7‑DC Monoclonal Antibody (Catalog # MAB1022), followed by Allophycocyanin-conjugated Anti-Rat IgG Secondary Antibody (Catalog # F0113). View our protocol for Staining Membrane-associated Proteins.

PD-L2/B7-DC/PDCD1LG2 Antibody (AP-MAB0877) - NBP1-06698 from Novus Biologicals

Prices $349.00
Sizes 500 µg
Host Rat
Clonality Monoclonal
Clone AP-MAB0877

PD-L2/B7-DC/PDCD1LG2 Antibody (TY25) - NB100-65332 from Novus Biologicals

Prices $279.00
Sizes 125 µg
Host Rat
Clonality Monoclonal
Clone TY25

PD-L2/B7-DC/PDCD1LG2 Antibody (122) - NBP1-43116 from Novus Biologicals

Prices $259.00, $299.00, $489.00
Sizes 50 µg, 100 µg, 500 µg
Host Rat
Clonality Monoclonal
Clone 122
Flow Cytometry: PD-L2/B7-DC/PDCD1LG2 Antibody (122) [NBP1-43116] - Analysis using the FITC conjugate of NBP1-43116. Staining of In vitro BALB/c mouse bone marrow-derived dendritic cells with 0.25 ug of Rat IgG2a kappa Isotype Control FITC (open histogram) or 0.25 ug of Anti-Mouse CD273 (B7-DC) FITC (filled histogram).

PD-L2/B7-DC/PDCD1LG2 Antibody [Biotin] - BAF1022 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

PD-L2/B7-DC/PDCD1LG2 Antibody [Fluorescein] - FAB1022F from Novus Biologicals

Host Goat
Clonality Polyclonal

PD-L2/B7-DC/PDCD1LG2 Antibody [PE] - FAB1022P from Novus Biologicals

Host Goat
Clonality Polyclonal

PD-L2/B7-DC/PDCD1LG2 Antibody (AP-MAB0877) [Alexa Fluor (R) 700] - NBP1-06698AF700 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone AP-MAB0877

PD-L2/B7-DC/PDCD1LG2 Antibody (AP-MAB0877) [Alexa Fluor (R) 647] - NBP1-06698AF647 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone AP-MAB0877

PD-L2/B7-DC/PDCD1LG2 Antibody (AP-MAB0877) [Alexa Fluor (R) 488] - NBP1-06698AF488 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone AP-MAB0877

PD-L2/B7-DC/PDCD1LG2 Antibody (AP-MAB0877) [Alexa Fluor (R) 405] - NBP1-06698AF405 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone AP-MAB0877

PD-L2/B7-DC/PDCD1LG2 Antibody (AP-MAB0877) [DyLight 350] - NBP1-06698UV from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone AP-MAB0877

PD-L2/B7-DC/PDCD1LG2 Antibody (AP-MAB0877) [DyLight 488] - NBP1-06698G from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone AP-MAB0877

PD-L2/B7-DC/PDCD1LG2 Antibody (AP-MAB0877) [7C] - NBP1-06698V2 from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone AP-MAB0877

PD-L2/B7-DC/PDCD1LG2 Antibody (AP-MAB0877) [DyLight 755] - NBP1-06698IR from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone AP-MAB0877

PD-L2/B7-DC/PDCD1LG2 Antibody (AP-MAB0877) [DyLight 405] - NBP1-06698V from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone AP-MAB0877

PD-L2/B7-DC/PDCD1LG2 Antibody (AP-MAB0877) [PE] - NBP1-06698PE from Novus Biologicals

Host Rat
Clonality Monoclonal
Clone AP-MAB0877
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