C5AR1

Gene Symbol	C5AR1
Entrez Gene	728
Alt Symbol	C5A, C5AR, C5R1, CD88
Species	Human
Gene Type	protein-coding
Description	complement component 5a receptor 1
Other Description	C5a anaphylatoxin chemotactic receptor 1|C5a anaphylatoxin receptor|C5a ligand|C5a-R|complement component 5 receptor 1
Swissprots	P21730
Accessions	AAD14919 AAO65969 CAB37830 EAW57470 EAW57471 P21730 BC008982 AAH08982 BE042476 BI916506 BM830753 BT007358 AAP36022 DQ891757 ABM82683 DQ894940 ABM85866 M62505 AAA62831 X57250 CAA40530 XM_005259190 XP_005259247 XM_011527247 XP_011525549 NM_001736 NP_001727
Function	Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520). {ECO:0000269|PubMed:10636859, ECO:0000269|PubMed:15153520, ECO:0000269|PubMed:1847994, ECO:0000269|PubMed:7622471, ECO:0000269|PubMed:8182049, ECO:0000269|PubMed:9553099}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:12464600}; Multi-pass membrane protein {ECO:0000255}. Cytoplasmic vesicle {ECO:0000269|PubMed:12464600}. Note=Phosphorylated C5aR colocalizes with ARRB1 and ARRB2 in cytoplasmic vesicles. {ECO:0000269|PubMed:12464600}.
Top Pathways	Complement and coagulation cascades, Staphylococcus aureus infection, Neuroactive ligand-receptor interaction

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human C5AR1 Gene cDNA Clone - orb142117 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human-C5AR1-cDNA-Clone - DC02551 from Abgent, a WuXi AppTec company Prices $472.50 Sizes 10 µg Species Human Accession BC008982

Human Complement Component C5aR1 (NP_001727) VersaClone cDNA - RDC0104 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

Mouse Complement Component C5aR1 (NP_031603) VersaClone cDNA - RDC0105 from R&D Systems Prices $199.00 Sizes 10 µg Species Mouse

C5AR1 - MBS1276679 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC008982

Human C5a anaphylatoxin receptor 1 Gene ORF cDNA clone in cloning vector - HG12154-G from Sino Biological Species Human

Human C5a anaphylatoxin receptor 1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG12154-NY from Sino Biological Species Human

Human C5a anaphylatoxin receptor 1 Gene ORF cDNA clone expression plasmid, N-His tag - HG12154-NH from Sino Biological Species Human

Human C5a anaphylatoxin receptor 1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG12154-ACR from Sino Biological Species Human

Human C5a anaphylatoxin receptor 1 Gene ORF cDNA clone expression plasmid, C-His tag - HG12154-CH from Sino Biological Species Human

Human C5a anaphylatoxin receptor 1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG12154-NF from Sino Biological Species Human

Human C5a anaphylatoxin receptor 1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG12154-NM from Sino Biological Species Human

Human C5a anaphylatoxin receptor 1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12154-CF from Sino Biological Species Human

Human C5a anaphylatoxin receptor 1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG12154-CM from Sino Biological Species Human

Human C5a anaphylatoxin receptor 1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG12154-CY from Sino Biological Species Human

Human C5a anaphylatoxin receptor 1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG12154-ACG from Sino Biological Species Human

Human C5a anaphylatoxin receptor 1 Gene ORF cDNA clone expression plasmid - HG12154-UT from Sino Biological Species Human

Human PROL1 ORF clone(NM_021225.4) - CDCL185858 from Creative biogene Species Human

Human C5AR1 ORF Clone(NM_001736.3) - CDCR281398 from Creative biogene Species Human

Human C5AR1 ORF Clone (BC008982) - CDCS410408 from Creative biogene Species Human Accession P21730

Human C5AR1 ORF clone (BC008982) - CDCB160008 from Creative biogene Species Human

Human C5AR1 cDNA Clone(NM_001736.3) - CDFH002384 from Creative biogene Species Human

Human PROL1 cDNA Clone(NM_021225.4) - CDFG003294 from Creative biogene Species Human

Search more