Gene Symbol |
Fa2h
|
Entrez Gene |
338521
|
Alt Symbol |
FAAH, Faxdc1, G630055L08Rik
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
fatty acid 2-hydroxylase
|
Other Description |
fatty acid alpha-hydroxylase|fatty acid hydroxylase domain containing 1
|
Swissprots |
Q8R0V1 Q2M2M0 Q5MPP0 Q8R0M0 Q8BTH1 Q5RL53
|
Accessions |
EDL11497 EDL11498 Q5MPP0 AK033736 AK090338 BAC41174 AK161502 BAE36428 AY660882 AAV70494 BB076849 BC026400 AAH26400 BC026629 AAH26629 BC046985 AAH46985 BC111912 AAI11913 BC128080 AAI28081 BC128081 AAI28082 CJ152901 NM_178086 NP_835187
|
Function |
Required for alpha-hydroxylation of free fatty acids and the formation of alpha-hydroxylated sphingolipids. {ECO:0000269|PubMed:15658937, ECO:0000269|PubMed:16998236}.
|
Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000269|PubMed:15658937}; Multi-pass membrane protein {ECO:0000269|PubMed:15658937}. Microsome membrane {ECO:0000269|PubMed:15658937}; Multi-pass membrane protein {ECO:0000269|PubMed:15658937}.
|
Tissue Specificity |
Detected in brain and skin (at protein level). Detected in brain white matter, cerebellum forebrain, stomach, kidney, skin and testis. Detected in oligodendrocytes. {ECO:0000269|PubMed:15658937, ECO:0000269|PubMed:16998236}.
|