Gene Symbol | Fa2h |
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Entrez Gene | 338521 |
Alt Symbol | FAAH, Faxdc1, G630055L08Rik |
Species | Mouse |
Gene Type | protein-coding |
Description | fatty acid 2-hydroxylase |
Other Description | fatty acid alpha-hydroxylase|fatty acid hydroxylase domain containing 1 |
Swissprots | Q8R0V1 Q2M2M0 Q5MPP0 Q8R0M0 Q8BTH1 Q5RL53 |
Accessions | EDL11497 EDL11498 Q5MPP0 AK033736 AK090338 BAC41174 AK161502 BAE36428 AY660882 AAV70494 BB076849 BC026400 AAH26400 BC026629 AAH26629 BC046985 AAH46985 BC111912 AAI11913 BC128080 AAI28081 BC128081 AAI28082 CJ152901 NM_178086 NP_835187 |
Function | Required for alpha-hydroxylation of free fatty acids and the formation of alpha-hydroxylated sphingolipids. {ECO:0000269|PubMed:15658937, ECO:0000269|PubMed:16998236}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:15658937}; Multi-pass membrane protein {ECO:0000269|PubMed:15658937}. Microsome membrane {ECO:0000269|PubMed:15658937}; Multi-pass membrane protein {ECO:0000269|PubMed:15658937}. |
Tissue Specificity | Detected in brain and skin (at protein level). Detected in brain white matter, cerebellum forebrain, stomach, kidney, skin and testis. Detected in oligodendrocytes. {ECO:0000269|PubMed:15658937, ECO:0000269|PubMed:16998236}. |
FA2H CRISPR/Cas9 KO Plasmid (m) - sc-436124 from Santa Cruz Biotechnology
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FA2H HDR Plasmid (m) - sc-436124-HDR from Santa Cruz Biotechnology
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FA2H Double Nickase Plasmid (m) - sc-436124-NIC from Santa Cruz Biotechnology
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FA2H Double Nickase Plasmid (m2) - sc-436124-NIC-2 from Santa Cruz Biotechnology
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FA2H CRISPR Activation Plasmid (m) - sc-436124-ACT from Santa Cruz Biotechnology
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FA2H CRISPR Activation Plasmid (m2) - sc-436124-ACT-2 from Santa Cruz Biotechnology
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FA2H Lentiviral Activation Particles (m) - sc-436124-LAC from Santa Cruz Biotechnology
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FA2H Lentiviral Activation Particles (m2) - sc-436124-LAC-2 from Santa Cruz Biotechnology
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FA2H siRNA (m) - sc-144999 from Santa Cruz Biotechnology
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FA2H shRNA Plasmid (m) - sc-144999-SH from Santa Cruz Biotechnology
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FA2H shRNA (m) Lentiviral Particles - sc-144999-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN30887 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND30887 from Sigma-Aldrich
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FA2H siRNA (Mouse) - CRN4727 from Cohesion Biosciences
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FA2H - MBS8232060 from MyBioSource
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shRNA set against Mouse FA2H (NM_178086.3) - SHH288557 from Creative biogene
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shRNA set against Mouse Fa2h(NM_178086.3) - SHH043787 from Creative biogene
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Mouse FA2H siRNA - orb294202 from Biorbyt
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FA2H shRNA Plasmid (Mouse) - CHN4727 from Cohesion Biosciences
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FA2H miRNA 3'UTR clone - MiUTR1M-04552 from Creative biogene
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