| Gene Symbol | Ifne |
|---|---|
| Entrez Gene | 230405 |
| Alt Symbol | Ifn-tau-1, Ifne1, Ifnt1, Infe1 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | interferon epsilon |
| Other Description | IFN-epsilon|interferon epsilon 1|interferon epsilon-1|interferon tau-1 |
| Swissprots | Q80ZF2 |
| Accessions | CAA38558 Q80ZF2 AY190044 AAO38685 BC104376 AAI04377 BC104377 AAI04378 NM_177348 NP_796322 |
| Function | Type I interferon required for maintaining basal levels of IFN-regulated genes, including 2'-5'-oligoadenylate synthetase, IRF7 and ISG15, in the female reproductive tract. Directly mediates protection against viral, including HSV-2, and bacterial, including Chlamydia muridarum, genital infections. {ECO:0000269|PubMed:23449591}. |
| Subcellular Location | Secreted {ECO:0000305}. |
| Tissue Specificity | Expressed at very high levels in uterus and, at much lower levels, in ovary and cervix. Very low levels, if any, in other organs. In the endometrium, expressed in the luminal and glandular epithelial cells (at protein level). {ECO:0000269|PubMed:15233997, ECO:0000269|PubMed:23449591}. |
| Top Pathways | Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, RIG-I-like receptor signaling pathway |
Anti-IFNE / Interferon Epsilon Antibody (Biotin) - LS-C318062 from LifeSpan Bioscience
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Anti-IFNE / Interferon Epsilon Antibody (HRP) - LS-C318063 from LifeSpan Bioscience
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Anti-IFNE / Interferon Epsilon Antibody - LS-C318065 from LifeSpan Bioscience
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Anti-IFNE / Interferon Epsilon Antibody (FITC) - LS-C319012 from LifeSpan Bioscience
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Interferon epsilon antibody (HRP) - orb240999 from Biorbyt
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Interferon epsilon Antibody - abx109922 from Abbexa
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Interferon epsilon Antibody (Biotin) - abx105571 from Abbexa
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Interferon epsilon Antibody (FITC) - abx106989 from Abbexa
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Interferon epsilon Antibody (HRP) - abx108410 from Abbexa
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Interferon epsilon, Polyclonal Antibody - MBS1491059 from MyBioSource
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Interferon epsilon, Polyclonal Antibody - MBS1490037 from MyBioSource
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Interferon epsilon, Polyclonal Antibody - MBS1489362 from MyBioSource
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Interferon epsilon, Polyclonal Antibody - MBS1491412 from MyBioSource
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Ifne Antibody - CSB-PA800374LA01MO from Cusabio
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Ifne Antibody,HRP conjugated - CSB-PA800374LB01MO from Cusabio
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Ifne Antibody,FITC conjugated - CSB-PA800374LC01MO from Cusabio
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Ifne Antibody,Biotin conjugated - CSB-PA800374LD01MO from Cusabio
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Interferon epsilon antibody (FITC) - orb240998 from Biorbyt
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Interferon epsilon antibody (Biotin) - orb240997 from Biorbyt
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