CYP11A1

Gene Symbol CYP11A1
Entrez Gene 1583
Alt Symbol CYP11A, CYPXIA1, P450SCC
Species Human
Gene Type protein-coding
Description cytochrome P450, family 11, subfamily A, polypeptide 1
Other Description cholesterol 20-22 desmolase|cholesterol monooxygenase (side-chain cleaving)|cholesterol side-chain cleavage enzyme, mitochondrial|cytochrome P450 11A1|cytochrome P450(scc)|cytochrome P450, subfamily XIA (cholesterol side chain cleavage)|cytochrome P450C11A1|steroid 20-22-lyase
Swissprots Q15081 A8K8D5 P05108 Q8N1A7 G3XAD7 Q16805 B3KPU8
Accessions ABC86898 CAA28965 CAA32471 EAW99341 EAW99342 P05108 AI149078 AK056794 BAG51810 AK225715 AK292300 BAF84989 AK292301 BAF84990 AK293204 BAG56744 AK293211 BAG56751 AK300178 BAG61957 AK310362 AY603498 BC032329 AAH32329 BX398579 DA010417 DQ891578 ABM82504 DQ894771 ABM85697 M14565 AAA52162 M28253 AAA36404 NM_000781 NP_000772 NM_001099773 NP_001093243
Function Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone. {ECO:0000269|PubMed:21636783}.
Subcellular Location Mitochondrion membrane.
Top Pathways Steroid hormone biosynthesis, Ovarian steroidogenesis

CYP11A1 (D8F4F) Rabbit mAb - 14217 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D8F4F
Western blot anlaysis of extracts from NCI-H295R cells, MLTC-1 cells, and various tissues using CYP11A1 (D8F4F) Rabbit mAb.

CYP11A1 Antibody - 12491 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal

CYP11A1 (C-16) - sc-18043 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

CYP11A1 (H-165) - sc-292456 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

CYP11A1 (D-16) - sc-18040 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CYP11A1 antibody - ab75497 from Abcam

Prices $392.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry with HK2 cells.

Anti-CYP11A1 antibody - ab175408 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CYP11A1 antibody (ab175408) at 1/500 dilution + HepG2 cell lysate

Anti-CYP11A1 antibody - ab67355 from Abcam

Prices $378.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-CYP11A1 antibody (ab67355) at 1/500 dilutionLane 1 : CYP11A1 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-CYP11A1 antibody - ab79820 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CYP11A1 antibody (ab79820) at 1/50 dilution + HepG2 cell lysate at 35 µg

Anti-CYP11A1 antibody - ab86357 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CYP11A1 antibody (ab86357) at 1 µg/mlLane 1 : HeLa (Human epithelial carcinoma cell line) Whole Cell LysateLane 2 : Brain (Human) Tissue Lysate - adult normal tissue (ab29466)Lane 3 : Testis (Human) Tissue Lysate - adult normal tissue (ab30257)Lane 4 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate Lane 5 : Liver (Human) Tissue Lysate - adult normal tissue (ab29889)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) (ab65484) at 1/3000 dilution (Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP))developed using the ECL techniquePerformed under reducing conditions.

Anti-P450SCC / CYP11A1 Antibody (aa288-337) IHC-plus™ - LS-B3997 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CYP11A1 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3997 concentration 5 ug/ml.

Anti-P450SCC / CYP11A1 Antibody (aa507-521) - LS-C312850 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
P450SCC / CYP11A1 antibody. IHC(F): Human Placenta Tissue.

Anti-P450SCC / CYP11A1 Antibody (aa78-418) IHC-plus™ - LS-B11607 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-P450SCC / CYP11A1 Antibody (aa241-481) IHC-plus™ - LS-B11699 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-P450SCC / CYP11A1 Antibody (aa398-447) - LS-C291850 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-P450SCC / CYP11A1 Antibody - LS-C310058 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-P450SCC / CYP11A1 Antibody - LS-C307833 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-P450SCC / CYP11A1 Antibody (aa457-502) - LS-C313725 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-P450SCC / CYP11A1 Antibody - LS-C192748 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of HepG2 cell lines, using CYP11A1 antibody.

Anti-P450SCC / CYP11A1 Antibody (HRP) - LS-C318643 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-P450SCC / CYP11A1 Antibody (aa88-120) - LS-C99457 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of anti-CYP11A1 Antibody in HepG2 cell line lysates (35 ug/lane). CYP11A1(arrow) was detected using the purified antibody.

Anti-P450SCC / CYP11A1 Antibody (FITC) - LS-C318644 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-P450SCC / CYP11A1 Antibody (Biotin) - LS-C318645 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-P450SCC / CYP11A1 Antibody - LS-C319057 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Cholesterol side-chain cleavage enzyme, mitochondrial antibody at 2 ug/ml with rat adrenal gland secondary Goat polyclonal to rabbit at 1:10000 dilution predicted band size: 60 KDa observed band size: 60 KDa.

Anti-P450SCC / CYP11A1 Antibody (aa53-66) - LS-C343893 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
CYP11A1 antibody Western blot. All lanes: Anti CYP11A1 at 0.5 ug/ml. Lane 1: Rat Testis Tissue Lysate at 50 ug. Lane 2: Mouse Testis Tissue Lysate at 50 ug. Lane 3: Mouse Brain Tissue Lysate at 50 ug. Predicted band size: 60 kD. Observed band size: 60 kD.
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