CAV3

Gene Symbol CAV3
Entrez Gene 859
Alt Symbol LGMD1C, LQT9, VIP-21, VIP21
Species Human
Gene Type protein-coding
Description caveolin 3
Other Description M-caveolin|caveolin-3
Swissprots Q3T1A4 A8K777 P56539
Accessions AAC39758 AAG02025 EAW63945 EAW63946 P56539 AA993189 AF036365 AAC39756 AF043101 AAC14931 AK291892 BAF84581 BC069368 AAH69368 BC102033 AAI02034 BC102036 AAI02037 BC102037 AAI02038 BF310794 BX114193 Y14747 CAA75042 NM_001234 NP_001225 NM_033337 NP_203123
Function May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Membrane, caveola {ECO:0000250}; Peripheral membrane protein {ECO:0000250}. Note=Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity). {ECO:0000250}.
Tissue Specificity Expressed predominantly in muscle. {ECO:0000269|PubMed:9545514}.
Top Pathways Focal adhesion, Endocytosis, Bacterial invasion of epithelial cells, Proteoglycans in cancer

caveolin-3 (A-3) - sc-5310 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
caveolin-3 (A-3): sc-5310. Western blot analysis of caveolin-3 expression in SJRH30 whole cell lysate.

caveolin-3 (C-2) - sc-55518 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
caveolin-3 (C-2): sc-55518. Western blot analysis of caveolin-3 expression in SJRH30 whole cell lysate.

caveolin-3 (E-12) - sc-30752 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

caveolin-3 (H-100) - sc-28828 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

caveolin-3 (N-18) - sc-7665 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
caveolin-3 (N-18): sc-7665. Western blot analysis of caveolin-3 expression in C2C12 whole cell lysate.

caveolin-3 (I-16) - sc-5437 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

caveolin-3 (P-18) - sc-30753 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Caveolin-3 antibody - ab2912 from Abcam

Prices $400.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of Caveolin-3 in HeLa Cells. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) (right panel) or with ab2912 at a dilution of 1:20 overnight at 4 C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody. Caveolin-3 staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Images were taken at 60X magnification.

Anti-Caveolin-3 antibody - ab125229 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Caveolin-3 antibody [EPR11082] - ab173575 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11082
All lanes : Anti-Caveolin-3 antibody [EPR11082] (ab173575) at 1/1000 dilutionLane 1 : Human Skeletal Muscle LysateLane 2 : Fetal Heart LysateLysates/proteins at 10 µg per lane.

Anti-Caveolin-3 antibody [EPR11083] - ab171752 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11083
All lanes : Anti-Caveolin-3 antibody [EPR11083] (ab171752) at 1/1000 dilutionLane 1 : Human skeletal muscle lysateLane 2 : Human fetal heart lysateLane 3 : Mouse muscle lysateLysates/proteins at 10 µg per lane.

Anti-Caveolin-3 antibody - Caveolae Marker - ab30750 from Abcam

Prices $394.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Caveolin-3 antibody - Caveolae Marker (ab30750) at 1 µg/mlLane 1 : Skeletal Muscle (Human) Tissue Lysate - adult normal tissue (ab29330)Lane 2 : Heart (Human) Tissue Lysate - adult normal tissue (ab29431)Lane 3 : Skeletal Muscle (Mouse) Tissue Lysate (ab29711)Lane 4 : Skeletal Muscle (Rat) Tissue Lysate - normal tissue (ab29376)Lysates/proteins at 20 µg per lane.SecondaryIRDye 680 Conjugated Goat Anti-Rabbit IgG (H+L) at 1/10000 dilutionPerformed under reducing conditions.

Anti-CAV3 / Caveolin 3 Antibody (aa1-18) - LS-C21396 from LifeSpan Bioscience

Prices $665.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CAV3 / Caveolin 3 Antibody (aa1-18) - LS-C78006 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CAV3 / Caveolin 3 Antibody (aa109-128) - LS-C312681 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
WB of CAV3 / Caveolin 3 antibody. Lane 1: U87 Cell Lysate. Lane 2: HELA Cell Lysate. Lane 3: MCF-7 Cell Lysate.

Anti-CAV3 / Caveolin 3 Antibody (clone 1B9) - LS-C139464 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B9
Detection limit for recombinant GST tagged CAV3 is 0.3 ng/ml as a capture antibody.

Anti-CAV3 / Caveolin 3 Antibody (aa1-83, clone 682708) - LS-C149896 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 682708
Caveolin-3 in Human Skeletal Muscle. Caveolin-3 was detected in immersion fixed paraffin-embedded sections of human skeletal muscle using Mouse Anti-Human Caveolin-3 Monoclonal Antibody at 15 ug/ml overnight at 4°C. Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic. Tissue was stained using Anti-Mouse HRP-DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to sarcolemma of muscle cells.

Anti-CAV3 / Caveolin 3 Antibody (aa19-41) IHC-plus™ - LS-B1589 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-CAV3 / Caveolin 3 antibody IHC of human breast, adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1589 concentration 5 ug/ml.

Anti-CAV3 / Caveolin 3 Antibody (aa5-31) - LS-C99234 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human Skeletal muscle reacted with CAV3 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-CAV3 / Caveolin 3 Antibody (N-Terminus) IHC-plus™ - LS-B1513 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-CAV3 / Caveolin 3 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1513 concentration 5 ug/ml.

Anti-CAV3 / Caveolin 3 Antibody (aa5-18) IHC-plus™ - LS-B8308 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-Caveolin 3 antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8308 dilution 3.75 ug/ml.

Caveolin-3 Antibody - NB110-5029 from Novus Biologicals

Prices $179.00, $329.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Caveolin-3 Antibody [NB110-5029] - Analysis of rat cardiac muscle protein extract.

Caveolin-3 Antibody (682708) - MAB6706 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 682708
Western blot shows lysates of human heart tissue, human skeletal muscle tissue, rat heart tissue, rat skeletal muscle tissue, and mouse heart tissue. PVDF Membrane was probed with 0.5 µg/mL of Mouse Anti-Human Caveolin-3 Monoclonal Antibody (Catalog # MAB6706) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for Caveolin-3 at approximately 20 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Caveolin-3 Antibody - NBP1-28917 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: Caveolin-3 Antibody [NBP1-28917] - Analysis of Caveolin 3 in Human Heart lysate (35ug protein in RIPA buffer) using this antibody at 0.3 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence.

Caveolin-3 Antibody - H00000859-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Caveolin 3 Antibody [H00000859-A01] - Western Blot analysis of CAV3 expression in SJCRH30 ( Cat # L027V1 ).
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