CAPN2

Gene Symbol CAPN2
Entrez Gene 824
Alt Symbol CANP2, CANPL2, CANPml, mCANP
Species Human
Gene Type protein-coding
Description calpain 2, (m/II) large subunit
Other Description CANP 2|M-calpain|calcium-activated neutral proteinase 2|calpain 2, large [catalytic] subunit|calpain 2, large subunit|calpain M-type|calpain large polypeptide L2|calpain, large polypeptide L2|calpain-2 catalytic subunit|calpain-2 large subunit|millimolar-calpain
Swissprots Q8WU26 A6NDG7 Q16738 E7ES58 Q9HBB1 B7ZA96 P17655 Q6PJT3
Accessions AAA52760 AAV80421 EAW93249 EAW93250 EAW93251 P17655 AB209855 BAD93092 AF261089 AAF99682 AI089162 AK023851 AK055046 AK056838 AK097247 BAG53441 AK124751 BAC85936 AK297800 BAG60139 AK303952 BAG64879 AK315179 BAG37620 AK316211 BAH14582 BC007686 AAH07686 BC011828 AAH11828 BC021303 AAH21303 DA448245 DQ893312 ABM84238 DQ893620 ABM84546 EU176804 ABW03605 M23254 AAA35645 XM_011544286 XP_011542588 NM_001146068 NP_001139540 NM_001748 NP_001739
Function Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). {ECO:0000269|PubMed:17650508}.
Subcellular Location Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon Ca(2+) binding.
Tissue Specificity Ubiquitous.
Top Pathways Apoptosis, Focal adhesion, Alzheimer's disease, Protein processing in endoplasmic reticulum

CAPN2 293 Cell Lysate - 400651 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

Calpain 2 Overexpression Lysate (Native) - NBL1-08680 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg

CAPN2 Over-expression Lysate Product - GWB-E62CF8 from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Panoply™ Human CAPN2 Knockdown Stable Cell Line - CSC-DC002347 from Creative biogene

Category Cell Line
Species Human

Human CAPN2 Knockout Cell Line-HEK293T - CSC-RT1228 from Creative biogene

Category Cell Line
Species Human

CAPN2 KO Cell Lysate-HEK293T - CLKO-1081 from Creative biogene

Category Cell Lysate
Search more