CAPN2

Gene Symbol	CAPN2
Entrez Gene	824
Alt Symbol	CANP2, CANPL2, CANPml, mCANP
Species	Human
Gene Type	protein-coding
Description	calpain 2, (m/II) large subunit
Other Description	CANP 2|M-calpain|calcium-activated neutral proteinase 2|calpain 2, large [catalytic] subunit|calpain 2, large subunit|calpain M-type|calpain large polypeptide L2|calpain, large polypeptide L2|calpain-2 catalytic subunit|calpain-2 large subunit|millimolar-calpain
Swissprots	Q8WU26 A6NDG7 Q16738 E7ES58 Q9HBB1 B7ZA96 P17655 Q6PJT3
Accessions	AAA52760 AAV80421 EAW93249 EAW93250 EAW93251 P17655 AB209855 BAD93092 AF261089 AAF99682 AI089162 AK023851 AK055046 AK056838 AK097247 BAG53441 AK124751 BAC85936 AK297800 BAG60139 AK303952 BAG64879 AK315179 BAG37620 AK316211 BAH14582 BC007686 AAH07686 BC011828 AAH11828 BC021303 AAH21303 DA448245 DQ893312 ABM84238 DQ893620 ABM84546 EU176804 ABW03605 M23254 AAA35645 XM_011544286 XP_011542588 NM_001146068 NP_001139540 NM_001748 NP_001739
Function	Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). {ECO:0000269|PubMed:17650508}.
Subcellular Location	Cytoplasm. Cell membrane. Note=Translocates to the plasma membrane upon Ca(2+) binding.
Tissue Specificity	Ubiquitous.
Top Pathways	Apoptosis, Focal adhesion, Alzheimer's disease, Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Calpain 2 peptide - ab41302 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Calpain 2 peptide - ab41303 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Calpain 2 peptide - ab41304 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Calpain 2 peptide - ab44836 from Abcam Category Peptide Prices $181.00 Sizes 100 µg

Human Calpain 2 full length protein - ab114344 from Abcam Category Protein Prices $420.00 Sizes 10 µg Source Wheat germ Species Human

Human Calpain 2 full length protein - ab172812 from Abcam Category Protein Prices $210.00 Sizes 10 µg Source E. coli Species Human

Rat Calpain 2 peptide - ab99036 from Abcam Category Peptide

Recombinant Human Calpain 2 Protein - H00000824-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant human Calpain-2 catalytic subunit (OPCA00033) - OPCA00033 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Human

Bovine Calpain-2 Catalytic Subunit protein - orb80997 from Biorbyt Category Protein Prices $366.00, $400.00, $612.00 Sizes 5 μg, 2 μg, 10 μg Source Bovine Myocardium

Human Calpain-2 catalytic subunit protein - orb163525 from Biorbyt Category Protein Prices $408.00, $595.00, $2,074.00, $2,933.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

Human CAPN2 protein - orb244069 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Calpain 1 protein - 30R-2409 from Fitzgerald Category Protein Prices $525.00 Sizes 100 µg Species Human

Calpain-2 - H00000824-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Calpain-2 - H00000824-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CAPN2, Human, Recombinant - 19-CG02 from ARP American Research Products Category Protein Prices $169.00 Sizes 10 µg Source E. coli Species Human

CAPN2 fusion protein - Ag2029 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

CAPN2 - PRPS-337 from NeoScientific Category Protein Prices $351.00, $637.00 Sizes 5 µg, 10 µg Source Bovine Myocardium.

Calpain-2 Peptide - 350554 from ABBIOTEC Category Peptide Prices $50.00 Sizes 100 µg

Recombinant Human CAPN2 Protein - BP000482-CG02 from Syd Labs Category Protein Prices $180.00, $528.00, $2,880.00 Sizes 10 µg, 50 µg, 1 mg Source E. coli-derived. Species Human

Bovine Calpain-2 Catalytic Subunit - BP000482-PRO-330 from Syd Labs Category Protein Prices $175.00, $270.00, $490.00 Sizes 2 µg, 5 µg, 10 µg Source Bovine Myocardium-derived. Species Bovine

m-Calpain - GWB-33B130 from Genway Biotech Category Protein Prices $245.00, $375.00, $665.00 Sizes 2 μg, 5 μg, 10 μg Source Cow (Myocardium)

Recombinant Human CAPN2 - CAPN2-27400TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human CAPN2, GST-tagged - CAPN2-10702H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human CAPN2, His-tagged - CAPN2-120H from Creative Biomart Category Protein Source E. coli Species Human

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